A computer-aided diagnosis system to screen for osteoporosis using dental panoramic radiographs
A computer-aided diagnosis system to screen for osteoporosis using dental panoramic radiographs
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DOI：
10.1259/dmfr/68621207
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发表时间：
2008-07-01
影响因子：
3.3
通讯作者：
Tanimoto, K.
中科院分区：
文献类型：
--
作者：
Nakamoto, T.;Taguchi, A.;Tanimoto, K.
目的：在牙科全景X线片上检测到下颌骨下皮质的侵蚀对于识别绝经后低骨密度（BMD）或骨质疏松症是有用的。本研究的目的是开发一个计算机辅助诊断（CAD）系统，自动确定否定全景X线片上的下颌骨皮质侵蚀，并评估该CAD系统的有效性。基于数学形态学开发了一个CAD系统，用于识别绝经后妇女的低骨密度或骨质疏松症，基于世界卫生组织的标准，下颌骨皮质骨的骨内膜边缘是否被侵蚀。使用100张全景X光片，使用二分2 x 2表格计算阳性风险结果的灵敏度、特异性、预测值、准确性和可能性。对低骨密度妇女的敏感性和特异性分别为76.8%和61.1%，阳性预测值和阴性预测值分别为90.0%和36.7%，准确性为74.0%，阳性风险的可能性为1.96。对骨质疏松症的诊断价值分别为94.4%和43.8%，阳性预测值和阴性预测值分别为48.6%和93.3%，准确率为62.0%，阳性风险似然率为1.68。我们的研究结果表明，CAD系统应用于牙科全景X线片可能是有用的，以确定后，低骨密度或骨质疏松的绝经期妇女。
Objectives: An eroded inferior cortex of the mandible detected on dental panoramic radiographs is useful for identifying post-menopausal won-ten with low skeletal bone mineral density (BMD) or osteoporosis. The purposes of this study were to develop a computer-aided diagnosis (CAD) system that automatically determines cortical erosion of the mandible on denial panoramic radiographs and to assess the validation of this CAD system.Methods: A CAD system was developed based on mathematical morphology for identifying post-menopausal women with low skeletal BMD or osteoporosis, based on World Health Organization criteria, by identifying whether the endosteal margin of mandibular cortical bone was eroded. The sensitivity, specificity, predictive value, accuracy and likelihood for a positive risk result were calculated using dichotomous 2 x 2 tables using 100 panoramic radiographs.Results: For identifying women with low skeletal BMD, the sensitivity and specificity were 76.8% and 61.1%, respectively, the positive and negative predictive values were 90.0% and 36.7%, accuracy was 74.0% and the likelihood for positive risk was 1.96. The respective values for identifying women with osteoporosis were 94.4% and 43.8%, the positive and negative predictive values were 48.6% and 93.3%, respectively, the accuracy was 62.0% and the likelihood for positive risk was 1.68.Conclusion: Our results suggest that a CAD system applied to dental panoramic radiographs may be useful for identifying post-menopausal women with low skeletal BNID or osteoporosis.