Future Therapies of Hepatic Encephalopathy.
Future Therapies of Hepatic Encephalopathy.
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DOI：
10.1016/j.cld.2024.02.002
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发表时间：
2024-05
影响因子：
5.1
通讯作者：
Adam P Buckholz;Robert S Brown
中科院分区：
文献类型：
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作者：
Adam P Buckholz;Robert S Brown
随着对 HE 的病理生理学、诱发因素和各种临床表现的了解越来越深入，对更好、更精确的治疗方案的需求也越来越大。如前所述，86 理想的治疗方案应考虑患者个体特征并直接解决 HE 的多因素性质。一般而言，目前的乳果糖和利福昔明治疗方案只能解决有限范围的问题，效果并不统一，并且可能无法解决问题。
As the pathophysiology, predisposing factors, and various clinical presentations of HE become better understood, the need for better and more precise therapeutic options grows. As previously posited, 86 an ideal treatment regimen would take into account individual patient characteristics and directly address the multifactorial nature of HE. In general, the current armamentarium of lactulose and rifaximin addresses only a limited scope of the problem, is not uniformly effective, and may not be