Interphase chromosome-specific multicolor banding (ICS-MCB): A new tool for analysis of interphase chromosomes in their integrity

Interphase chromosome-specific multicolor banding (ICS-MCB): A new tool for analysis of interphase chromosomes in their integrity
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DOI:
10.1016/j.bioeng.2007.05.003
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发表时间:
2007-10-01
期刊:
BIOMOLECULAR ENGINEERING
影响因子:
--
通讯作者:
Yurov, Yuri B.
Yurov, Yuri B.
中科院分区:
其他
文献类型:
--
作者:
Iourov, Ivan Y.;Liehr, Thomas;Yurov, Yuri B.

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对间期染色体完整性的生物医学研究受到技术限制的阻碍。我们介绍了一种技术,使用显微解剖为基础的工程DNA探针和荧光标记染色体显带,可以研究间期染色体的组织,数量和重排体细胞。(c)2007 Elsevier B.V.保留所有权利。
Biomedical research of interphase chromosomes in their integrity is hindered by technical limitations. We introduce a technology using microdissection-based engineering of DNA probes and fluorescence multicolor chromosome banding that allows studying interaphase chromosome organization, numbers and rearrangements in somatic cells. (c) 2007 Elsevier B.V. All rights reserved.