T2-prepared SSFP improves diagnostic confidence in edema imaging in acute myocardial infarction compared to turbo spin echo
T2-prepared SSFP improves diagnostic confidence in edema imaging in acute myocardial infarction compared to turbo spin echo
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DOI：
10.1002/mrm.21215
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发表时间：
2007-05-01
影响因子：
3.3
通讯作者：
Arai, Andrew E.
中科院分区：
文献类型：
--
作者：
Kellman, Peter;Aletras, Anthony H.;Arai, Andrew E.
急性心肌梗死（MI）水肿的T-2加权MRI提供了一种区分急性和慢性MI以及评估梗死风险区域的方法。传统的水肿的T-2加权成像使用涡轮自旋回波（TSE）读数与暗血准备。暗血TSE方法的临床应用可能受到伪影的限制，例如由于通过平面运动导致的后壁信号丢失，以及由于血液停滞导致的明亮的内膜下伪影。使用T-2准备的SSFP读数的单次激发成像提供了暗血TSE的替代方案，并且可以在自由呼吸期间进行。我们假设T-2制备的SSFP是一种比暗血TSE更可靠的MI患者水肿成像方法。在心肌梗死患者（22例急性和9例慢性心肌梗死病例）中，在造影剂给药和延迟增强成像之前使用两种方法进行T-2加权成像。31例病例中有3例使用TSE进行的T-2加权图像未做出诊断，而另外6例被评为具有诊断质量的病例却做出了错误的诊断。在所有31例病例中，T-2准备的SSFP图像被评定为诊断质量，正确区分急性或慢性MI，并正确确定冠状动脉区域。自由呼吸T-2准备的SSFP提供了急性MI的T-2加权图像，与传统的黑血TSE相比，伪影更少，诊断准确性更高。
T-2-weighted MRI of edema in acute myocardial infarction (MI) provides a means of differentiating acute and chronic MI, and assessing the area at risk of infarction. Conventional T-2-weighted imaging of edema uses a turbo spin-echo (TSE) readout with darkblood preparation. Clinical applications of darkblood TSE methods can be limited by artifacts such as posterior wall signal loss due to through-plane motion, and bright subendocardial artifacts due to stagnant blood. Single-shot imaging with a T-2-prepared SSFP readout provides an alternative to dark-blood TSE and may be conducted during free breathing. We hypothesized that T-2-prepared SSFP would be a more reliable method than dark-blood TSE for imaging of edema in patients with MI. In patients with MI (22 acute and nine chronic MI cases), T-2-weighted imaging with both methods was performed prior to contrast administration and delayed enhancement imaging. The T-2-weighted images using TSE were nondiagnostic in three of 31 cases, while six additional cases rated as being of diagnostic quality yielded incorrect diagnoses. In all 31 cases the T-2-prepared SSFP images were rated as diagnostic quality, correctly differentiated acute or chronic MI, and correctly determined the coronary territory. Free-breathing T-2-prepared SSFP provides T-2-weighted images of acute MI with fewer artifacts and better diagnostic accuracy than conventional dark-blood TSE.