Study of Interaction of Laser with Tissue Using Monte Carlo Method for 1064nm Neodymium-Doped Yttrium Aluminium Garnet (Nd:YAG) Laser.
Study of Interaction of Laser with Tissue Using Monte Carlo Method for 1064nm Neodymium-Doped Yttrium Aluminium Garnet (Nd:YAG) Laser.
复制标题
使用蒙特卡罗方法研究 1064nm 掺钕钇铝石榴石 (Nd:YAG) 激光器的激光与组织相互作用。
DOI：
10.22037/2010.v6i1.5077
复制
发表时间：
2015
影响因子：
1.5
通讯作者：
M. Abazari
中科院分区：
文献类型：
--
作者：
A. Majdabadi;M. Abazari
介绍
激光吸脂术是目前最常见的美容手术之一。这种新方法减少了传统吸脂术的缺点，包括失血，皮肤松弛和恢复时间长。新的吸脂方法的好处，包括创伤小，出血和皮肤收紧证明这些方法优于传统的机械方法。激光与脂肪组织的相互作用在这些新手术的开发中起着至关重要的作用，因为这种相互作用同时导致皮肤层的收缩和小血管的凝固，从而实现皮肤紧致和减少出血。
方法
激光脂肪分解使用插入1 mm金属套管内的激光纤维，将激光辐射直接传递到目标组织。激光脂解具有波长依赖性机制，组织加热和因此热效应通过目标组织细胞吸收辐射来实现，导致它们的温度升高和它们的体积膨胀。我们采用蒙特卡罗方法模拟光子在生物组织中的传播。该方法通过随机抽样物理变量的概率分布来模拟物理变量。我们还使用Comsol Multiphysics软件模拟了温升和组织加热。
结论
由于最佳和安全的激光脂肪分解操作高度依赖于组织和激光辐射的光学特性，如激光能量密度，激光功率等，因此对这些过程的物理理解至关重要。在这项研究中，我们的目的是评估这些重要参数的影响。
结果
我们的模拟结果证明，1064 nm钕掺杂钇铝石榴石（Nd：YAG）具有良好的渗透深度到脂肪组织，可以达到更深层的脂肪组织。我们看到，这个波长也导致了良好的温度上升;在用这个波长照射脂肪组织后，我们观察到组织在允许值（50-65°C）内加热，这就是为什么这个波长被广泛用于激光脂解手术。
INTRODUCTION
Liposuction using laser is now one of the most common cosmetic surgery. This new method has minimized the disadvantages of the conventional liposuction including blood loss, skin laxity and long recovery time. Benefits of the new liposuction methods which include less trauma, bleeding and skin tightening prove the superiority of these methods over the traditional mechanical methods. Interaction of laser with fat tissue has the vital role in the development of these new procedures because this interaction simultaneously results in retraction of skin layers and coagulation of small blood vessels so skin tightening and less bleeding is achieved.
METHOD
Laser lipolysis uses a laser fiber inserted inside a metal cannula of 1 mm delivering the laser radiation directly to the target tissue. Laser lipolysis has a wavelength dependent mechanism, tissue heating and therefor thermal effects are achieved through absorption of radiation by the target tissue cells, causing their temperature to rise and their volumes to expand. We used Monte Carlo (MC) method to simulate the photons propagation within the tissue. This method simulates physical variables by random sampling of their probability distribution. We also simulated temperature rise and tissue heating using Comsol Multiphysics software.
CONCLUSION
Because optimum and safe laser lipolysis operation highly depends on optical characteristics of both tissue and laser radiation such as laser fluence, laser power and etc. having physical understanding of these procedures is of vital importance. In this study we aim to evaluate the effects of these important parameters.
RESULTS
Findings of our simulation prove that 1064 nm Neodymium-Doped Yttrium Aluminium Garnet (Nd:YAG) has good penetration depth into fat tissue and can reach inside the deeper layers of fat tissue. We see that this wavelength also resulted in good temperature rise; after irradiation of fat tissue with this wavelength we observed that tissue heated in permitted values (50-65°C), this is why this wavelength is widely used in laser lipolysis operations.
影响因子：
6.1
作者：
WANG, LH;JACQUES, SL;ZHENG, LQ
通讯作者：
ZHENG, LQ