Complicated Carotid Artery Plaques as a Cause of Cryptogenic Stroke
Complicated Carotid Artery Plaques as a Cause of Cryptogenic Stroke
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DOI：
10.1016/j.jacc.2020.09.532
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发表时间：
2020-11-10
影响因子：
24
通讯作者：
Saam, Tobias
中科院分区：
文献类型：
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作者：
Kopczak, Anna;Schindler, Andreas;Saam, Tobias
背景 高达 30% 的患者中，缺血性中风的根本病因仍不清楚。 目的 本研究探讨了复杂（美国心脏协会 - VI 型病变）非狭窄颈动脉斑块 (CAP) 在隐源性中风 (CS) 中的因果作用。 方法 CAPIAS（急性中风颈动脉斑块成像）是一项观察性多中心研究，前瞻性招募年龄超过 49 岁的急性中风患者。脑磁共振成像 (MRI) 和单侧或双侧 CAP（>= 2 mm，NASCET [北美症状性颈动脉内膜切除术试验] 仅限于单颈动脉区域的缺血性中风
BACKGROUND The underlying etiology of ischemic stroke remains unknown in up to 30% of patients.OBJECTIVES This study explored the causal role of complicated (American Heart Association-lesion type VI) non-stenosing carotid artery plaques (CAPs) in cryptogenic stroke (CS).METHODS CAPIAS (Carotid Plaque Imaging in Acute Stroke) is an observational multicenter study that prospectively recruited patients aged older than 49 years with acute ischemic stroke that was restricted to the territory of a single carotid artery on brain magnetic resonance imaging (MRI) and unilateral or bilateral CAP (>= 2 mm, NASCET [North American Symptomatic Carotid Endarterectomy Trial]