Dynamics of diabetes and obesity: Epidemiological perspective.

Dynamics of diabetes and obesity: Epidemiological perspective.
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DOI:
10.1016/j.bbadis.2017.01.016
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发表时间:
2017-05
期刊:
Biochimica et biophysica acta. Molecular basis of disease
影响因子:
--
通讯作者:
Reddy PH
Reddy PH
中科院分区:
其他
文献类型:
--
作者:
Boles A;Kandimalla R;Reddy PH

文献摘要

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这篇综述文章的目的是了解目前世界各地关于肥胖、糖尿病和治疗途径的文献。糖尿病是一种慢性生活方式疾病,影响全球数百万人,是我们社会的主要健康问题。糖尿病和肥胖症与各种疾病有关,包括不可改变和可改变的风险因素。早期可检测的标志物并没有很好地建立来检测糖尿病前期,因此,它变成了糖尿病。对几项已发表的流行病学研究进行了评估,并对结果进行了总结。来自已发表研究的资源用于确定糖尿病前期的标准,饮食在糖尿病前期的作用以及与糖尿病前期相关的潜在风险和特征。需要采取预防策略来防治糖尿病。被诊断为糖尿病前期的个体需要详细的教育,需要充分了解危险因素,并有能力管理糖尿病。现有的干预措施包括慢性病自我管理计划,生活方式干预和药理学策略。肥胖在导致糖尿病前期和糖尿病方面起着很大的作用。对现有流行病学研究数据的批判性分析表明,需要进行更多的研究来确定干预措施的功效。
The purpose of this review article is to understand the current literature on obesity, diabetes and therapeutic avenues across the world. Diabetes is a chronic lifestyle condition that affects millions of people worldwide and it is a major health concern in our society. Diabetes and obesity are associated with various conditions, including non-modifiable and modifiable risk factors. Early detectable markers are not well established to detect pre-diabetes and as a result, it becomes diabetes. Several published epidemiological studies were assessed and the findings were summarized. Resources from published studies were used to identify criteria used for pre-diabetes, the role of diet in pre-diabetics and potential risks and characteristics associated with pre-diabetes. Preventive strategies are needed to combat diabetes. Individuals diagnosed with pre-diabetes need detailed education, need to fully understand the risk factors and have the ability to manage diabetes. Interventions exist that include chronic disease self-management programs, lifestyle interventions and pharmacological strategies. Obesity plays a large role in causing pre-diabetes and diabetes. Critical analysis of existing epidemiological research data suggests that additional research is needed to determine the efficacy of interventions.