Predictors of Health-Related Quality of Life for Mental Health Status in Patients After Carotid Endarterectomy.
Predictors of Health-Related Quality of Life for Mental Health Status in Patients After Carotid Endarterectomy.
复制标题
颈动脉内膜切除术后患者心理健康状况的健康相关生活质量的预测因素。
DOI：
10.1016/j.wneu.2019.02.060
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发表时间：
2019
影响因子：
2
通讯作者：
Qu Lefeng
中科院分区：
文献类型：
--
作者：
Jiang Qingjun;Lin Tao;Qu Lefeng
目的评价颈动脉狭窄患者的健康相关生活质量，探讨影响颈动脉内膜切除术(CEA)患者心理健康状况的预测因素。收集临床资料和人口学资料进行Logistic回归分析。采用简明一般健康调查问卷(SF-36)和最低临床重要度差异问卷对CEA患者进行心理健康状况评估。基线时，颈动脉疾病患者的SF-36躯体成分总分(60.10±26.3)分和精神成分总分(59.9±23.1)分显著低于城市人群(P<；0.001)。CEA后，SF-36的PCS(62.5±21.7)分和MCS(68.4±18.7)分明显升高。然而，只有MCS的改善达到了最小的临床重要差异。多因素Logistic回归分析显示，对侧狭窄≥50%(优势比[OR]0.266，95%可信区间[CI]0.141~0.517)和声音嘶哑(OR 0.160，95%可信区间0.040~0.644)对MCS有负面影响。头晕改善对MCS有正向影响(OR 2.882，95%CI 1.569~5.298)。结论对侧狭窄、头晕改善、声音嘶哑可能是影响CEA术后患者心理健康状况的预测因素。
ObjectiveTo evaluate the health-related quality of life (HRQoL) in patients with carotid stenosis and identify the predictive factors that affect the mental health status in patients after carotid endarterectomy (CEA).MethodsA retrospective study was conducted of all patients presenting with carotid stenosis treated with CEA. Clinical data and demographics were collected for logistic regression analysis. The Short-Form General Health Survey Questionnaire (SF-36) and minimum clinically important difference were used to evaluate the mental health status of patients after CEA.ResultsBetween January 2015 and September 2017, a total of 224 patients were enrolled in this study. At baseline, mean SF-36 scores for physical component summary (PCS) (60.1 ± 26.3) and mental component summary (MCS) (59.9 ± 23.1) were significantly lower in patients with carotid disease than the urban population (P< 0.001). After CEA, the SF-36 scores for PCS (62.5 ± 21.7) and MCS (68.4 ± 18.7) were increased. However, only the improvement of MCS achieved minimum clinically important difference. After multiple logistic regression analysis, contralateral stenosis ≥50% (odds ratio [OR] 0.266, 95% confidence interval [CI] 0.141–0.517) and hoarseness (OR 0.160, 95% CI 0.040–0.644) had negative effects on MCS. Dizziness improvement had positive effects on MCS (OR 2.882, 95% CI 1.569–5.298).ConclusionsContralateral stenosis, dizziness improvement, and hoarseness may be the predictive factors that affect the mental health status in patients after CEA.