Cognitive remediation and vocational rehabilitation for schizophrenia

Cognitive remediation and vocational rehabilitation for schizophrenia
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DOI:
10.1093/schbul/sbi038
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发表时间:
2005-10-01
影响因子:
6.6
通讯作者:
Bell, MD
Bell, MD
中科院分区:
医学1区
文献类型:
--
作者:
Wexler, BE;Bell, MD

文献摘要

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认知缺陷是精神分裂症和其他主要精神疾病的核心和令人衰弱的方面。尽管它们在很大程度上对药物治疗无效,但多项研究现在已经表明,行为干预可以显著而持久地改善认知能力。我们将回顾我们过去10年的工作,证明认知补救治疗与工作治疗或支持性就业相结合,可以在认知和工作功能方面带来大规模、持久和临床相关的改善。虽然我们将参考其他人在这些相同领域的工作,但这并不是对这些研究领域的一般性审查。相反,我们的目标是为我们的研究进展提供理论基础,描述方法,总结结果,以便读者能够理解、批评和改进我们所做的工作。
Cognitive deficits are a central and debilitating aspect of schizophrenia and other major mental illnesses. Although they are largely refractory to pharmacotherapy, multiple studies have now shown that large and lasting improvements in cognition can result from behavioral interventions. We will review our work over the past 10 years demonstrating that cognitive remediation treatment together with work therapy or supported employment can lead to large, lasting, and clinically relevant improvements in cognition and work functioning. While we will make some references to the work of others in these same areas, this is not a general review of these areas of research. Instead, the goal is to provide the rationale for the progression of our studies, describe the methods, and summarize the results, so that readers may understand, critique, and improve upon what we have done.