Five year survival and later outcome of patients with X-ray occult lung cancer detected by sputum cytology

Five year survival and later outcome of patients with X-ray occult lung cancer detected by sputum cytology
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DOI:
10.1016/s0169-5002(00)00190-2
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发表时间:
2000-10-01
期刊:
影响因子:
5.3
通讯作者:
Saccomanno, G
Saccomanno, G
中科院分区:
医学2区
文献类型:
--
作者:
Bechtel, JJ;Petty, TL;Saccomanno, G

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背景资料:先前报道了一组51例经痰细胞学检查和支气管镜检查确诊的X线隐匿性肺癌患者。方法:所有患者均随访5年以上,并确定死亡原因。结果:27例切除治愈的患者实际5年生存率为74%,包括全因死亡。所有接受手术或放疗试图治愈的患者的5年生存率为54.3%。痰细胞学检查发现12例继发性癌症,其中8例死亡。结论:痰液细胞学检查可用于确定高风险患者的早期肺癌,其中治愈的机会是有利的。(C)2000年由Elsevier Science爱尔兰有限公司出版。
Background: A cohort of 51 consecutive patients with roentgenographically occult lung cancer, identified by sputum cytology and confirmed by bronchoscopy was reported previously. Methods: All patients have now been followed beyond 5 years and the causes of death ascertained. Results: The actual 5-year survival of 27 patients who were resected for cure was 74% including death for all causes. The 5-year survival of all patients who received either surgery or radiation in an attempt to cure was 54.3%. Twelve secondary cancers were found by sputum cytology; eight of these patients have died. Conclusions: Sputum cytology can be useful in the identification of early stage lung cancer in patients at high-risk where the chances of cure are favorable. (C) 2000 Published by Elsevier Science Ireland Ltd.