Familism and Inflammatory Processes in African American, Latino, and White Youth
Familism and Inflammatory Processes in African American, Latino, and White Youth
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DOI：
10.1037/hea0000715
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发表时间：
2019-04-01
影响因子：
4.2
通讯作者：
Miller, Gregory E.
中科院分区：
文献类型：
--
作者：
Chiang, Jessica J.;Chen, Edith;Miller, Gregory E.
目的：非洲裔美国人和拉丁裔美国人是美国最大的两个少数民族群体，与白人相比，这些少数民族群体在某些身体健康问题上面临不成比例的风险。然而，可能保护这些群体免受健康状况不佳的早期风险的因素并不完全清楚。强调家庭相互依存和承诺的家庭主义，在拉丁美洲和非洲裔美国家庭中更为普遍，可能是其中一个因素。目前的研究探讨了是否价值观和行为有关的家庭主义与炎症过程中的白色，非洲裔美国人和拉丁美洲青年的差异。方法：参与者是257名青年谁完成了家庭主义的价值观和行为的措施，其父母报告他们的种族。参与者还提供了血液样本，用于评估促炎细胞因子对细菌挑战的反应以及对皮质醇和白细胞介素（IL）-10抗炎特征的敏感性。结果：显着的家庭主义价值观和行为的种族相互作用。对于拉丁裔和非洲裔美国青年，但不是白色青年，更多的家庭主义价值观与更大的敏感性IL-10。此外，对于非洲裔美国青年，更多的家庭主义行为与细胞因子对细菌挑战的反应降低以及对皮质醇和IL-10的敏感性增加有关。相比之下，家庭主义行为与白色青年对皮质醇的敏感性较低相关，而与拉丁美洲青年的任何炎症结果无关。结论：这种模式的研究结果表明，对于非洲裔美国青年和拉丁美洲青年在某种程度上，家庭主义的价值观和行为可能是保护他们所面临的健康状况不佳的风险增加。
Objective: African Americans and Latinos make up the two largest minority groups in the United States, and compared with Whites, these ethnic minority groups face disproportionate risk for certain physical health problems. However, factors that may protect these groups against early risk for poor health are not entirely understood. Familism, which emphasizes family interdependence and commitment, and is more prevalent among Latino and African American families, may be one such factor. The current study examined whether values and behaviors related to familism were differentially associated with inflammatory processes among White, African American, and Latino youth. Method: Participants were 257 youth who completed measures of familism values and behaviors and whose parents reported on their ethnicity. Participants also provided blood samples for the assessment of proinflammatory cytokine responses to bacterial challenge and of sensitivity to anti-inflammatory features of cortisol and interleukin (IL)-10. Results: Significant familism values and behaviors by ethnicity interactions were observed. For Latino and African American youth but not for White youth, more familism values were associated with greater sensitivity to IL-10. Additionally, for African American youth, more familism behaviors were associated with decreased cytokine responses to bacterial challenge and greater sensitivity to cortisol and IL-10. By contrast, familism behaviors were associated with lower sensitivity to cortisol in White youth and were not associated with any inflammatory outcomes in Latino youth. Conclusion: This pattern of findings suggests that for African American youth and to some extent for Latino youth, familism values and behaviors may be protective against the elevated risk for poor health they face.