Assessing the Accuracy of the Modified Chinese Autism Spectrum Rating Scale and Social Responsiveness Scale for Screening Autism Spectrum Disorder in Chinese Children.
Assessing the Accuracy of the Modified Chinese Autism Spectrum Rating Scale and Social Responsiveness Scale for Screening Autism Spectrum Disorder in Chinese Children.
复制标题
评估改良中国自闭症谱系评定量表和社会反应量表筛查中国儿童自闭症谱系障碍的准确性
DOI：
10.1007/s12264-017-0114-5
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发表时间：
2017-04
影响因子：
5.6
通讯作者：
Xu X
中科院分区：
文献类型：
--
作者：
Zhou B;Zhou H;Wu L;Zou X;Luo X;Fombonne E;Wang Y;Yan W;Xu X
据报道，在世界许多地区，自闭症谱系障碍(ASD)的患病率正在迅速上升。然而，关于它在中国的患病率的数据在很大程度上是缺失的。在这里，我们通过与广泛用于ASD筛查的社会反应性量表(SRS)的比较，评估了新开发的ASD筛查工具的改良中文版--改良的中国自闭症谱系评定量表(MC-ASRS)在中国6-12岁儿童ASD筛查中的适用性。我们招募了1588名典型发育儿童和190名6-12岁ASD儿童的父母/照顾者来完成MC-ASRS和SRS，并评价了这两个量表在区分ASD儿童和典型发展儿童方面的有效性。结果显示，在受试者操作特性分析中，MC-ASRS的灵敏度、特异度和曲线下面积(均为0.95)与SRS一样好，有较好的假阴性率。这些结果表明，MC-ASRS是一种在中国普通人群中筛查ASD儿童的有前景的工具。
The reported prevalence of autism spectrum disorder (ASD) has been increasing rapidly in many parts of the world. However, data on its prevalence in China are largely missing. Here, we assessed the suitability of the modified Chinese version of a newly-developed ASD screening tool, the Modified Chinese Autism Spectrum Rating Scales (MC-ASRS) in screening for ASD in Chinese children aged 6–12 years, through comparison with the Social Responsiveness Scale (SRS) that has been widely used for ASD screening. We recruited the parents/caregivers of 1588 typically-developing children and 190 children with ASD aged 6–12 years to complete the MC-ASRS and SRS, and evaluated the validity of both scales in discriminating children with ASD from those developing typically. The results showed that MC-ASRS performed as well as SRS in sensitivity, specificity, and area-under-the-curve (both >0.95) in receiver operating characteristic analysis, with a fair false-negative rate. These results suggest that MC-ASRS is a promising tool for screening for children with ASD in the general Chinese population.