Emotional expression and diurnal cortisol slope in women with metastatic breast cancer in supportive-expressive group therapy: A preliminary study
Emotional expression and diurnal cortisol slope in women with metastatic breast cancer in supportive-expressive group therapy: A preliminary study
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DOI：
10.1016/j.biopsycho.2006.04.003
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发表时间：
2006-08-01
影响因子：
2.6
通讯作者：
Spiegel, David
中科院分区：
文献类型：
--
作者：
Giese-Davis, Janine;DiMiceli, Sue;Spiegel, David
我们研究了转移性乳腺癌患者在初始治疗期间的编码情绪表达及其与已知的早期死亡生理危险因素——异常的昼夜皮质醇斜率的关系。在64名转移性乳腺癌女性中，随机分配到支持表达组治疗（SET）的多地点临床干预试验中，29名子样本符合本研究的资格标准。在调整了说话时间、压抑-防御、焦虑以及压抑-防御和焦虑之间的相互作用后，我们测试了主要负面情绪（恐惧、悲伤和愤怒）表达的平均持续时间是否与更陡峭的日皮质醇斜率相关。我们发现，更陡峭的皮质醇斜率与更低的压抑防御和更大的初级负面情绪表达有关，这与先验假设一致。此外，我们还探讨了编码的积极影响、防御/敌对影响、克制愤怒以及主要消极影响和压抑-防御之间的相互作用是否解释了皮质醇昼夜模式的额外差异。(c) 2006 Elsevier B.V.版权所有
We examined coded emotional expression during an initial therapy session and its association with a known physiological risk factor for early death, aberrant diurnal cortisol slope, in women with metastatic breast cancer. Out of 64 women with metastatic breast cancer randomized to a multi-site clinical intervention trial of supportive-expressive group therapy (SET), a subsample of 29 met eligibility criteria for this study. We tested whether longer mean durations of primary negative affect (fear, sadness, and anger) expression were associated with steeper diurnal cortisol slopes after adjusting for speaking time, repressive-defensiveness, anxiety, and the interaction between repressive-defensiveness and anxiety. We found that steeper cortisol slopes were related to lower repressive-defensiveness and greater primary negative affect expression in line with a priori hypotheses. Additionally we explored whether coded positive affect, defensive/hostile affect, constrained anger, and the interaction between primary negative affect and repressive-defensiveness explained additional variance in diurnal cortisol patterns. (c) 2006 Elsevier B.V. All rights reserved.