Brain polarization of parietal cortex augments training-induced improvement of visual exploratory and attentional skills
Brain polarization of parietal cortex augments training-induced improvement of visual exploratory and attentional skills
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DOI：
10.1016/j.brainres.2010.06.053
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发表时间：
2010-08-19
期刊：
影响因子：
2.9
通讯作者：
Vallar, Giuseppe
中科院分区：
文献类型：
--
作者：
Bolognini, Nadia;Fregni, Felipe;Vallar, Giuseppe
最近的证据表明，当与皮层神经调节技术（如经颅直流电刺激（tDCS））相结合时，行为训练引起的行为收益最大化。在这里，我们通过研究将多感觉视野探索训练与后顶叶皮层（PPC）的tDCS相结合的效果来解决这种吸引人的方法的有效性。多感官视野探索训练是通过对视野进行系统的视听刺激进行视觉搜索的实践。神经功能未受损的参与者进行30分钟的双峰探索训练，同时接受阳极兴奋性PPC tDCS或假tDCS。在两个不同的实验中，左半球和右半球受到刺激。结果测量包括训练期间不同时间间隔的视觉探索速度，以及训练后对视觉扫描和视觉空间定向测试的影响。结果表明，与假tDCS相比，PPC tDCS应用于右半球，而不是左半球，增加了训练诱导的视觉探索行为改善。此外，在不同于视觉搜索的任务中，右PPC tDCS带来了隐蔽视觉定向的改善。在另一个实验中，我们证实，即使没有相关的训练，右顶叶tDCS本身也可以导致视觉搜索的增强。总的来说，当与视野探索训练任务相结合时，阳极PPC tDCS是一种很有前途的增强视觉空间能力的技术。(C) 2010 Elsevier B.V.版权所有
Recent evidence suggests that behavioural gains induced by behavioural training are maximized when combined with techniques of cortical neuromodulation, such as transcranial Direct Current Stimulation (tDCS). Here we address the validity of this appealing approach by investigating the effect of coupling a multisensory visual field exploration training with tDCS of the posterior parietal cortex (PPC). The multisensory visual field exploration training consisted in the practice of visual search through the systematic audio-visual stimulation of the visual field. Neurologically unimpaired participants performed a bimodal exploration training for 30 min, while simultaneously receiving anodal-excitatory PPC tDCS or sham tDCS. In two different experiments, the left and the right hemisphere were stimulated. Outcome measures included visual exploration speed at different time intervals during the training, and the post-training effects on tests assessing visual scanning and visuo-spatial orienting. Results show that PPC tDCS applied to the right, but not to the left, hemisphere increases the training-induced behavioural improvement of visual exploration, as compared to sham tDCS. In addition, right PPC tDCS brings about an improvement of covert visual orienting, in a task different from the visual search practice. In an additional experiment, we confirm that right parietal tDCS by itself, even without the associated training, can lead to enhancement of visual search. Overall, anodal PPC tDCS is a promising technique to enhance visuo-spatial abilities, when combined to a visual field exploration training task. (C) 2010 Elsevier B.V. All rights reserved.