Measurement of systemic oxygen delivery and inotropy in healthy term neonates with the Ultrasonic Cardiac Output Monitor (USCOM)
Measurement of systemic oxygen delivery and inotropy in healthy term neonates with the Ultrasonic Cardiac Output Monitor (USCOM)
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DOI：
10.1016/j.earlhumdev.2012.10.006
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发表时间：
2013-05-01
影响因子：
2.5
通讯作者：
Smith, Brendan E.
中科院分区：
文献类型：
--
作者：
He, Shao-Ru;Sun, Xin;Smith, Brendan E.
简介：本研究的目的是评估健康足月新生儿在出生后第一天和出生后前三天循环适应期间的Smith-Madigan收缩力（SMI）、Smith-Madigan收缩力指数（SMII）、氧输送（DO 2）和氧输送指数DO 2 I的正常值。使用超声心输出量监测仪（USCOM）无创测量了71名正常足月新生儿前三天的左心血流动力学。将其与脐带血血红蛋白浓度和脉搏血氧仪结合，计算DO 2和DO 2 I。结果：SMI和SMII在研究期间无明显变化，分别为154 ~ 168 mW/m2和694 ~ 731 mW/m2。平均（SD）DO 2和DO 2 I在3天内从131（63）ml/min和596（278）ml/m2/min显著下降至118（46）ml/min和517（173）ml/m2/min（p
Introduction: The aim of this study was to assess the normal values for Smith-Madigan inotropy (SMI), Smith-Madigan inotropy index (SMII), oxygen delivery (DO2) and oxygen delivery index DO2I in healthy term neonates on the first day of life and during circulatory adaptation over the first three days of life.Methods: Hemodynamics of the left heart were measured non-invasively in 71 normal full-term neonates over the first three days using the Ultrasonic Cardiac Output Monitor (USCOM). This was combined with hemoglobin concentration from umbilical cord blood and pulse oximetry to calculate DO2 and DO2I. Blood pressure was measured using automated oscillometry and combined with the hemodynamic measures and hemoglobin concentration using the Smith-Madigan method to calculate inotropy (SMI) and inotropy index (SMII).Results: SMI and SMII showed no significant change during the study period, ranging from 154 to 168 mW and 694 to 731 mW/m(2). Mean (SD) DO2 and DO2I showed a significant fall over three days from 131 (63) ml/min and 596 (278) ml/m(2)/min to 118 (46) ml/min and 517 (173) ml/m(2)/min (p