Recording and measuring the interior features of intracranial aneurysms removed at autopsy: method and initial findings.
Recording and measuring the interior features of intracranial aneurysms removed at autopsy: method and initial findings.
复制标题
记录和测量尸检时切除的颅内动脉瘤的内部特征：方法和初步发现。
作者：
S. P. Black;H. Leo;W. Carson
决定颅内动脉瘤行为的因素之一是其体积与开口大小之间的关系。本文所述的研究方法是用于定义人类关系的手段。这是一项针对未破裂动脉瘤的尸检研究。该方案的核心是动脉瘤内部的合成橡胶模型。模型是在正常动脉压下制作的，这样未破裂的动脉瘤就可以重新扩张到逼真的大小和形状。从标本中完整取出铸型后，通过与打开的动脉瘤进行比较，验证其上记录的管腔特征。现在只使用石膏，从动脉通过颈部切开腔室。通过数学方法将其划分为许多较小的可测量形式来确定孔口面积。通过流体置换技术确定腔室体积。这两个测量都是用放大镜和工程仪器进行的。破裂或血栓形成的动脉瘤的铸型提供了有用的形态学信息，但测量价值有限。的技术进行了描述，并给出了初步结果的例子。
Among the factors that determine the behavior of an intracranial aneurysm is the relationship between its volume and the size of the orifice. The investigative method described herein is the means being used to define that relationship in humans. It is a postmortem study that focuses on unruptured aneurysms. Central to the protocol was a synthetic rubber cast of the aneurysm's interior. The cast was made under normal arterial pressure so that unruptured aneurysms were reexpanded to lifelike size and shape. After the cast was removed intact from the specimen, the lumenal features recorded upon it were verified by comparison with the opened aneurysm. Working now only with the cast, the chamber was cut from the artery through its neck. The orifice area was determined by dividing it, mathematically, into many smaller, measurable forms. Chamber volume was ascertained by a fluid displacement technique. Both measurements were made with magnification and engineering instruments. Casts of ruptured or thrombosed aneurysms gave helpful morphological information, but were of limited value for measurement. The techniques are described, and examples of the initial results are presented.