CHANNEL CATFISH VIRUS - A NEW TYPE OF HERPESVIRUS
CHANNEL CATFISH VIRUS - A NEW TYPE OF HERPESVIRUS
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DOI：
10.1016/0042-6822(92)90056-u
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发表时间：
1992-01-01
期刊：
影响因子：
3.7
通讯作者：
DAVISON, AJ
中科院分区：
文献类型：
--
作者：
DAVISON, AJ
疱疹病毒是一种大型双链DNA病毒，感染从鱼类到人类的脊椎动物。感染高等脊椎动物（鸟类和哺乳动物）的疱疹病毒之间令人信服的遗传关系已经通过比较从DNA序列预测的蛋白质而得到证实，并被解释为从共同祖先进化的结果。为了评估低等脊椎动物的疱疹病毒如何符合该方案，对癍点叉尾鱼病毒的134，226-bp基因组进行了测序。遗传比较表明，必须考虑这种病毒的独立进化起源。这些发现影响了目前对疱疹病毒进化和基因功能的认识。
Herpesviruses are large double-stranded DNA viruses which infect vertebrates from fish to man. Convincing genetic relationships between herpesviruses that infect higher vertebrates (birds and mammals) have been demonstrated previously by comparing proteins predicted from DNA sequences and have been interpreted as a result of evolution from a common ancestor. In order to evaluate how herpesviruses of lower vertebrates fit into this scheme, the 134,226-bp genome of channel catfish virus was sequenced. Genetic comparisons indicate that a separate evolutionary origin for this virus must be considered. The findings impact upon current perceptions of herpesvirus evolution and gene function.