Depiction of achilles tendon microstructure in vivo using high-resolution 3-dimensional ultrashort echo-time magnetic resonance imaging at 7 T.
Depiction of achilles tendon microstructure in vivo using high-resolution 3-dimensional ultrashort echo-time magnetic resonance imaging at 7 T.
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DOI：
10.1097/rli.0000000000000025
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发表时间：
2014-05
影响因子：
6.7
通讯作者：
Krug R
中科院分区：
文献类型：
--
作者：
Han M;Larson PE;Liu J;Krug R
目的：探讨利用7T高分辨率三维超短回波时间磁共振成像(MRI)技术显示跟腱内部结构的可行性。在我们的UTE成像中，使用了最小相位射频脉冲和各向异性视场3D径向采集来最小化回波时间和扫描时间。每8个轮辐采集施加一个脂肪饱和脉冲，以减少脂肪造成的模糊和化学位移伪影，并提高肌腱信号的动态范围。5名健康志愿者和1名患者接受了各向同性空间分辨率高达0.6 mm的扫描。对脂肪抑制的UTE图像进行定性评估，并与非脂肪抑制的UTE图像和较长的回声时间图像进行比较。高分辨率UTE成像能够可视化跟腱的微结构。脂肪抑制大大改善了对内部结构的描述。UTE图像显示跟腱和肌腱附着处的纤维软骨中有束状图案。在一名出生后接受肌腱延长手术的患者中，有清晰的肌腱结构被破坏的描述。在7T的高分辨率脂肪抑制3D UTE成像允许在活体内评估跟腱的微结构。
To demonstrate the feasibility of depicting the internal structure of the Achilles tendon in vivo using high-resolution 3D ultrashort echo-time (UTE) magnetic resonance imaging (MRI) at 7T. For our UTE imaging, a minimum-phase radiofrequency pulse and an anisotropic field-of-view 3D radial acquisition were used to minimize the echo time and scan time. A fat saturation pulse was applied every eight spoke acquisitions to reduce blurring and chemical shift artifacts from fat and to improve dynamic range of the tendon signal. Five healthy volunteers and one patient were scanned with an isotropic spatial resolution of up to 0.6 mm. Fat-suppressed UTE images were qualitatively evaluated and compared to non-fat-suppressed UTE images and longer echo-time images. High-resolution UTE imaging was able to visualize the microstructure of the Achilles tendon. Fat suppression substantially improved the depiction of the internal structure. The UTE images revealed a fascicular pattern in the Achilles tendon and fibrocartilage at the tendon insertion. In a patient who had tendon elongation surgery after birth there was clear depiction of disrupted tendon structure. High-resolution fat-suppressed 3D UTE imaging at 7T allows for evaluation of the Achilles tendon microstructure in vivo.