Gait performance in relation to aortic pulse wave velocity, carotid artery elasticity and peripheral perfusion in healthy older adults
Gait performance in relation to aortic pulse wave velocity, carotid artery elasticity and peripheral perfusion in healthy older adults
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DOI：
10.1111/cpf.12019
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发表时间：
2013-07-01
影响因子：
1.8
通讯作者：
Gonzales, Joaquin U.
中科院分区：
文献类型：
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作者：
Gonzales, Joaquin U.
动脉硬化是一个众所周知的生理变化，随着年龄的增长，但血管老化的功能后果尚不清楚。本研究的目的是确定颈动脉股动脉脉搏波速度（PWV），颈动脉和股动脉和/或外周灌注的机械性能是否与使用400米步行试验测量的步态表现。21名无心血管疾病的健康老年人（68 +/-5岁）参加了这项研究。采用压平眼压计测量PWV，多普勒超声测量左颈总动脉和股总动脉血管壁特性，沿股动脉血流方向沿着。测试前2分钟的中位步行距离为585英尺，整体步态速度为1个中心点5 ms-1。步态表现与PWV呈负相关（距离：r=-0中心点51;速度：r=0中心点48; P
Arterial stiffening is a widely known physiological change that occurs with ageing, but the functional consequences of vascular ageing are unclear. The purpose of this study was to determine whether carotidfemoral pulse wave velocity (PWV), mechanical properties of the carotid and femoral arteries and/or peripheral perfusion was associated with gait performance measured using a 400-m walk test. Twenty-one healthy older (68 +/- 5years) adults without cardiovascular disease participated in this study. Applanation tonometry was used to measure PWV, and Doppler ultrasound was used to measure arterial wall properties of the left common carotid and common femoral artery along with femoral blood flow. The median walk distance in the first 2min of the test was 585ft, and the overall gait speed was 1 center dot 5ms1. Gait performance was inversely correlated with PWV (distance: r=-0 center dot 51; speed: r=0 center dot 48; P