Prescription rebellion: reduction of antibiotic use by small animal veterinarians

Prescription rebellion: reduction of antibiotic use by small animal veterinarians
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DOI:
10.1111/jsap.13098
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发表时间:
2020-01-14
影响因子:
1.6
通讯作者:
Jeffery, N.
Jeffery, N.
中科院分区:
农林科学3区
文献类型:
--
作者:
Allerton, F.;Jeffery, N.

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合理,或者更具体地说,减少抗生素的使用是兽医学(包括小动物实践)的一个长期主题。这些措施包括为不同的农业部门设定严格的抗生素使用目标,加强监测和基准,全面禁止在动物中使用任何新的抗菌药物,并限制在食用动物中使用最高优先级的至关重要的抗生素;抗生素的销售量下降了50%以上,动物中MDR细菌的发生率降低(Mevius & Heederik [34])。在考虑败血症的方法时,抗生素管理面临着患者护理的正面;管理压倒性的感染或优化抗生素的使用似乎需要矛盾的方法。许多其他抗生素都存在严重的不良反应,可能会对特定物种或品种产生更严重的影响;考虑不良反应特征是抗生素选择的重要步骤,并因患者而异。[摘自文章]
Rational, or more specifically, reduction in, antibiotic use is a long-standing theme in veterinary medicine, including small animal practice. These have included setting stringent antibiotic-usage targets for different agricultural sectors, increased monitoring and benchmarking, a full ban on the use of any new antibacterial drug in animals and a restriction of the use of highest priority critically important antibiotics in food animals; sales of antibiotics decreased by > 50% and the occurrence of MDR bacteria in animals reduced (Mevius & Heederik [34]). Antibiotic stewardship confronts patient care head-on when considering the approach to sepsis; managing an overwhelming infection or optimising antibiotic use seemingly warrant contradictory approaches. Serious adverse effects are recognised with many other antibiotics and can affect specific species or breeds more severely; consideration of the adverse effect profile is an important step in antibiotic selection and will vary by patient.[Extracted from the article]