A threshold gap size for in situ secondary caries lesion development
A threshold gap size for in situ secondary caries lesion development
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DOI：
10.1016/j.jdent.2018.10.014
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发表时间：
2019-01-01
影响因子：
4.4
通讯作者：
Huysmans, M. C. D. N. J. M.
中科院分区：
文献类型：
--
作者：
Maske, T. T.;Hollanders, A. C. C.;Huysmans, M. C. D. N. J. M.
目的：本研究调查了非常小的间隙在继发龋（SC）发展中的影响，并将阈值间隙大小与志愿者的龋活动水平联系起来。方法：15名志愿者戴着装有牙本质复合材料样品的改良咬合板，用不同的界面进行修复，持续21天。保税（B =用完全粘合剂程序修复的样品）、无粘合（NB =用复合树脂修复而无粘合剂程序）和30、60和90 μ m（无粘合剂程序且具有有意间隙）。将夹板浸入20%蔗糖溶液中（10分钟），每天8次。用横向波长独立显微放射照相术（T-WIM）对样品进行成像，并计算损伤深度和矿物质损失。结果：B组和NB组均无龋壁损伤形成，B组无龋壁损伤形成，B组无龋壁损伤形成。一般来说，故意的差距导致SC病变深度进展独立的龋齿活动水平的志愿者。两名志愿者未发现实质性壁病变。高活动组观察到在较大间隙中更深的病变趋势。结论：非常小的间隙周围或宽于30 μ m的发展SC独立于患者的龋齿活动水平，SC壁病变进展似乎与个体因素相关，即使在这种标准化原位模型中。独立于患者的龋齿活动水平，继发性龋壁损伤的阈值间隙大小似乎最多为30 μ m。
Objectives: This study investigated the influence of very small gaps in secondary caries (SC) development and additionally linked the threshold gap size with the caries activity level from volunteers.Methods: For 21 days, 15 volunteers wore a modified occlusal splint loaded with dentin-composite samples restored with different interfaces: bonded (B = samples restored with complete adhesive procedure), no-bonded (NB = restored with composite resin without adhesive procedure), and 30, 60 and 90 mu m (no adhesive procedure and with intentional gap). The splint was dipped in a 20% sucrose solution (10 min) 8 x per day. Samples were imaged with transversal wavelength independent microradiography (T-WIM) and lesion depth and mineral loss were calculated. Average wall lesion depth from each volunteer was determined and according to the values the volunteers were grouped as high, mid and low caries activity levels.Results: No wall lesion formation was observed in B and NB groups. In general, intentional gaps led to SC lesion depth progression independent of caries activity level of volunteers. No substantial wall lesions were found for two volunteers. A trend for deeper lesion in larger gaps was observed for the high activity group.Conclusion: Very small gaps around or wider than 30 mu m develop SC independent of the caries activity level of the patient and SC wall lesion progression seemed to be related to individual factors even in this standardized in situ model.Significance: Independently of caries activity level of the patient, the threshold gap size for secondary caries wall lesion seems to be 30 mu m at most.