How I treat patients with adult onset Still's disease in clinical practice
How I treat patients with adult onset Still's disease in clinical practice
复制标题
DOI：
10.1016/j.autrev.2017.07.017
复制
发表时间：
2017-10-01
影响因子：
13.6
通讯作者：
Modena, Vittorio
中科院分区：
文献类型：
--
作者：
Govoni, Marcello;Bortoluzzi, Alessandra;Modena, Vittorio
成人斯蒂尔病（AOSD）是一种病因不明的罕见全身性炎症性疾病，其特征在于几乎总是存在于患者中的四个主要体征：高热、关节痛（伴或不伴滑膜炎）、斑丘疹性橙红色一过性皮疹、显著白细胞增多伴嗜中性粒细胞增多。在这里，我们回顾了AOSD的临床特征，并描述了其管理的最佳实践方法，回顾了可用的指南和建议，并提供了专家的见解。(C)2017由Elsevier B.V.出版
Adult onset Still's disease (AOSD) is a rare systemic inflammatory disease of unknown etiology characterized by four cardinal signs which are almost always present in patients: high spiking fever, arthralgia (with or without synovitis), maculo-papular salmon-pink evanescent skin rash, striking leukocytosis with neutrophilia. Here, we review the clinical features of AOSD and describe the best practice approaches for its management, reviewing available guidelines and recommendations and providing experts' insights. (C) 2017 Published by Elsevier B.V.