The Chalder Fatigue Questionnaire is a valid and reliable measure of perceived fatigue severity in multiple sclerosis
The Chalder Fatigue Questionnaire is a valid and reliable measure of perceived fatigue severity in multiple sclerosis
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DOI：
10.1177/1352458515598019
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发表时间：
2016-04-01
影响因子：
5.8
通讯作者：
Moss-Morris, Rona
中科院分区：
文献类型：
--
作者：
Chilcot, Joseph;Norton, Sam;Moss-Morris, Rona
背景：疲劳是多发性硬化症（MS）最令人痛苦的症状之一。测量MS疲劳带来了许多挑战。目的：评价11项疲劳严重度量表--Chalder疲劳问卷（CFQ）在MS中的信度、内部信度、区分效度和变化敏感度。方法：采用问卷调查法，对11项疲劳严重度量表--Chalder疲劳问卷（CFQ）的因子结构效度、内部信度、区分效度和变化敏感度进行分析。合并了使用CFQ（n=444）研究MS疲劳的4项既往研究的数据。数据分析包括验证性因素分析，以确定因素结构和模型拟合，相关性，以评估判别效度和效应大小，以确定灵敏度changes.Results：一个双因素模型与一个一般的疲劳因素，将两个较小的组因素（精神和身体疲劳）有良好的模型拟合，并出现了最合适的因素结构的CFQ规模。CFQ有很高的内部一致性，表现出小到中度的相关性与疲劳和情绪的影响，并在低和高强度的行为interventions.Conclusions的变化是敏感的：CFQ测量复合的身体和精神疲劳的严重程度（即总分）是一个心理测量的声音测量疲劳的严重程度在MS。
Background: Fatigue is one of the most distressing symptoms of multiple sclerosis (MS). Measuring MS fatigue poses a number of challenges. Many measures confound definitions of severity and impact of fatigue and/or lack psychometric validation in MS.Objective: To evaluate the psychometric properties of an 11-item fatigue severity measure, the Chalder Fatigue Questionnaire (CFQ) in MS including validity of the factor structure, internal reliability, discriminant validity and sensitivity to change.Methods: Data were pooled from four previous studies investigating MS fatigue using the CFQ (n=444). Data analysis included confirmatory factor analysis to determine the factor structure and model fit, correlations to assess discriminant validity and effects sizes to determine sensitivity to change.Results: A bi-factor model with one general fatigue factor, incorporating two smaller group factors (mental and physical fatigue) had good model fit and appeared the most appropriate factor structure underlying the CFQ scale. The CFQ had high internal consistency, showed small to moderate correlations with impact of fatigue and mood, and was sensitive to change across low and high intensity behavioural interventions.Conclusions: The CFQ measuring a composite of physical and mental fatigue severity (i.e. a total score) is a psychometrically sound measure of fatigue severity in MS.