Colorectal Cancer Surgery in Elderly Patients: Presentation, Treatment, and Outcomes
Colorectal Cancer Surgery in Elderly Patients: Presentation, Treatment, and Outcomes
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DOI：
10.1007/dcr.0b013e3181a74d2e
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发表时间：
2009-07-01
影响因子：
3.9
通讯作者：
McLeod, R. S.
中科院分区：
文献类型：
--
作者：
Devon, K. M.;Vergara-Fernandez, O.;McLeod, R. S.
目得：本研究的目的是表征的演示文稿，护理，和结果的人年龄超过75岁，与人相比，50至74岁，选择为colorectal cancer.METHODS：患者年龄超过50岁，谁在西奈山医院1997年和2006年之间的结肠癌或直肠癌手术进行了鉴定。数据来自结直肠癌数据库以及办公室和医院记录。患者被分为两组：50至74岁和75岁及以上。结果：有623例患者在年轻组（平均年龄，62.6岁）和275在老年组（平均年龄，81.5岁）。住院死亡率在年轻组为1%，而在老年组为4.2%（P = 0.002）。年轻组和老年组的总体五年生存率分别为68.7%和57.3%，而结直肠癌特异性五年生存率无显著差异（74.0% vs. 74.7%）。两组之间有显着差异，就癌症的位置，美国麻醉医师协会的评分，阶段，比例检测到的筛选，住院时间，和使用chemotherapy.CONCLUSIONS：长期结直肠癌相关的结果在老年组是类似的结果在年轻患者，这表明，决定操作不应仅基于年龄。
PURPOSE: This study was designed to characterize the presentation, care, and outcomes of persons older than 75 years, compared with persons 50 to 74 years of age, selected for colorectal cancer.METHODS: Patients over the age of 50 years who had surgery for colon or rectal cancer at the Mount Sinai Hospital between 1997 and 2006 were identified. Data were obtained from a colorectal cancer database and from office and hospital records. Patients were assigned to two groups: 50 to 74 years old and 75 years and older.RESULTS: There were 623 patients in the younger group (mean age, 62.6 years) and 275 in the older group (mean age, 81.5 years). The in-hospital mortality rate was 1% in the younger group compared with 4.2% in the older (P = 0.002). The overall five-year survival was 68.7% and 57.3% in the younger and older groups, respectively, whereas colorectal cancer-specific five-year survival was not significantly different (74.0% vs. 74.7%). There were significant differences between the two groups with respect to cancer location, American Society of Anesthesiologists' score, stage, proportion detected by screening, length of stay, and use of chemotherapy.CONCLUSIONS: Long-term colorectal cancer-related outcomes in the older group are similar to the outcomes in younger patients, suggesting that the decision to operate should not be based on age alone.