Posterior ciliary artery circulation in health and disease - The Weisenfeld Lecture
Posterior ciliary artery circulation in health and disease - The Weisenfeld Lecture
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DOI：
10.1167/iovs.03-0469
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发表时间：
2004-03-01
影响因子：
4.4
通讯作者：
Hayreh, SS
中科院分区：
文献类型：
--
作者：
Hayreh, SS
睫状后动脉（PCA）循环是视神经乳头（ONH）的主要血液供应来源，它还供应脉络膜至赤道、视网膜色素上皮（RPE）、视网膜外130 μm（当存在睫状视网膜动脉时，该区域的整个视网膜厚度）以及睫状体和虹膜的内侧和外侧段。这使得PCA循环成为眼部和ONH循环的最重要部分。因此，PCA循环的紊乱可导致各种眼部和ONH血管疾病，引起不同程度的视力丧失。自1955年以来，我通过解剖、实验和临床研究，调查了健康和疾病中PCA循环的各个方面。本讲座的目的主要是总结这些研究的主要发现。审查近年来积累的关于这一问题的大量文献超出了本报告的范围。
The posterior ciliary artery (PCA) circulation is the main source of blood supply to the optic nerve head (ONH), and it also supplies the choroid up to the equator, the retinal pigment epithelium (RPE), the outer 130 μm of retina (and, when a cilioretinal artery is present, the entire thickness of the retina in that region), and the medial and lateral segments of the ciliary body and iris. That makes the PCA circulation the most important part of the ocular and ONH circulation. Therefore, disturbances in the PCA circulation can result in a variety of ocular and ONH vascular disorders, causing varying degrees of visual loss. I have investigated various aspects of the PCA circulation in health and disease by anatomic, experimental, and clinical studies since 1955. The objective of this lecture is essentially to summarize the main findings of those studies. It is beyond its scope to review the extensive literature on the subject that has accumulated over recent years.