Patients' perspectives of rheumatoid arthritis treatment: a questionnaire survey for the 2020 update of the Japan college of rheumatology clinical practice guidelines
Patients' perspectives of rheumatoid arthritis treatment: a questionnaire survey for the 2020 update of the Japan college of rheumatology clinical practice guidelines
复制标题
DOI：
10.1080/14397595.2021.1913276
复制
发表时间：
2021-05-15
影响因子：
2.2
通讯作者：
Harigai, Masayoshi
中科院分区：
文献类型：
--
作者：
Kojima, Masayo;Hasegawa, Mieko;Harigai, Masayoshi
目的 本研究旨在评估患者对其类风湿关节炎 (RA) 治疗的看法，并在 2020 年更新的日本风湿病学会临床实践指南中反映患者的观点。方法向日本风湿病友好协会会员1600名邮寄自填问卷，按年龄和地区随机抽取。结果 共有 1156 名患者填写了问卷（回复率为 72.3%；平均年龄为 63.0 +/- 11.9 岁）。与那些没有讨论或解释其目标的人（287 名受访者，24.8%）相比，那些报告与医生讨论过治疗目标的人（450 名受访者，38.9%）更有可能对他们当前的医疗护理感到满意（比值比，7.13；95% CI 4.72-10.8）。其益处超过了所有药物疗法（甲氨蝶呤、皮质类固醇、传统合成抗风湿药物、生物制剂、Janus 激酶抑制剂和抗 RANKL 抗体）的副作用。然而，虽然 74.2% 使用生物制剂的受访者认为“有利的方面超过不利的方面”，但大多数服用抗 RANKL 抗体的受访者 (69.2%) 感到不确定。结论 问卷成功收集了患者对其治疗的看法的信息。日本有必要进一步实施目标治疗，以提高患者满意度。
Objectives This study aimed to evaluate patients' opinions regarding their rheumatoid arthritis (RA) therapy and to reflect the patients' perspectives in the 2020 update of the Japan College of Rheumatology clinical practice guidelines. Methods A self-administered questionnaire was mailed to 1600 members of the Japan Rheumatology Friendship Association, who were randomly selected by age and prefecture. Results A total of 1156 patients returned the questionnaire (response rate, 72.3%; mean age, 63.0 +/- 11.9 years). Those who reported having discussed their treatment goals with their doctors (450 respondents, 38.9%) were more likely to be satisfied with their current medical care (odds ratio, 7.13; 95% CI 4.72-10.8) compared with those who had not discussed their goals nor had them explained (287 respondents, 24.8%). The benefits exceeded the adverse effects for all pharmacotherapy (methotrexate, corticosteroids, conventional synthetic antirheumatic drugs, biological agents, Janus kinase inhibitor, and anti-RANKL antibodies). However, while 74.2% of the respondents using biological agents perceived that 'the favorable aspects outweighed the unfavorable aspects,' most of those taking anti-RANKL antibodies (69.2%) felt uncertain. Conclusions The questionnaire successfully collected information regarding patients' perceptions regarding their therapy. Further implementation of treat-to-target is necessary in Japan to improve patient satisfaction.