Planning Study Size Based on Precision Rather Than Power
Planning Study Size Based on Precision Rather Than Power
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DOI：
10.1097/ede.0000000000000876
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发表时间：
2018-09-01
期刊：
影响因子：
5.4
通讯作者：
Greenland, Sander
中科院分区：
文献类型：
--
作者：
Rothman, Kenneth J.;Greenland, Sander
研究规模通常是基于统计能力来规划的，因此受到统计假设检验哲学的严重影响。一个有价值的替代方案是根据精确度来计划研究规模，例如，通过旨在获得目标效果的所需可信区间宽度。本文提出了根据基本流行病学效果指标的预期精确度来规划流行病学研究规模的公式。
Study size has typically been planned based on statistical power and therefore has been heavily influenced by the philosophy of statistical hypothesis testing. A worthwhile alternative is to plan study size based on precision, for example by aiming to obtain a desired width of a confidence interval for the targeted effect. This article presents formulas for planning the size of an epidemiologic study based on the desired precision of the basic epidemiologic effect measures.