Respiratory Motion-Resolved Compressed Sensing Reconstruction of Free-Breathing Radial Acquisition for Dynamic Liver Magnetic Resonance Imaging.
Respiratory Motion-Resolved Compressed Sensing Reconstruction of Free-Breathing Radial Acquisition for Dynamic Liver Magnetic Resonance Imaging.
复制标题
DOI：
10.1097/rli.0000000000000179
复制
发表时间：
2015-11
影响因子：
6.7
通讯作者：
Otazo R
中科院分区：
文献类型：
--
作者：
Chandarana H;Feng L;Ream J;Wang A;Babb JS;Block KT;Sodickson DK;Otazo R
证明使用呼吸运动分辨压缩感知（CS）重建（XD-GRASP）进行自由呼吸径向采集用于多相动态Gd-EOB-DTPA增强肝脏成像的可行性，并在相同患者中将图像质量与使用呼吸运动平均（GRASP）的CS重建和之前的传统屏气笛卡尔采样数据集（BH-VIBE）进行比较。在这项符合HIPAA的前瞻性研究中，16名受试者在Gd-EOB-DTPA注射期间接受了自由呼吸连续桡动脉采集，并且既往有BH-VIBE检查可用。采集的数据重建使用运动平均GRASP方法，其中连续的84个辐条被分组在每个对比增强阶段的时间分辨率为14秒。此外，通过使用名为XD-GRASP的压缩感知算法将每个对比度增强阶段分类为多个呼吸运动状态，从相同的k空间数据执行呼吸运动分辨重建，该算法利用对比度增强和呼吸状态维度的稀疏性沿着。对比增强动态多期XD-GRASP、GRASP和BH-VIBE图像被匿名化，以随机顺序汇集在一起，并提交给两名委员会认证的放射科医生进行图像质量的独立评估，分数越高表示检查越优化。（所有p<0.05）与GRASP相比，早期动脉的总体图像质量评分更高（阅片人1：4.3 ± 0.6 vs. 3.31 ± 0.6 ;阅片人2：3.81 ± 0.8 vs. 3.38 ± 0.9）和晚期动脉（阅片者1：4.5 ± 0.6 vs. 3.63 ± 0.6;阅片者2：3.56 ± 0.5 vs. 2.88 ± 0.7）两名阅片者的增强相位。XD-GRASP在门静脉期的总体图像质量评分也较高，阅片人1的评分具有显著性（4.44 ± 0.5 vs. 3.75 ± 0.8; p=0.002）。此外，对于早期（阅片人1：4.3±0.6 vs. 3.88±0.6;阅片人2：3.81±0.8 vs. 3.50±1.0）和晚期（阅片人1：4.5±0.6 vs. 3.44±0.6;阅片人2：3.56±0.5 vs. 2.94±0.9）动脉相位，XD-GRASP的总体图像质量评分高于BH-VIBE。自由呼吸运动分辨XD-GRASP重建为接受Gd-EOB-DTPA增强肝脏检查的患者提供诊断性高质量多相图像。
Demonstrate feasibility of free-breathing radial acquisition with respiratory motion-resolved compressed sensing (CS) reconstruction (XD-GRASP) for multiphase dynamic Gd-EOB-DTPA enhanced liver imaging, and compare image quality to CS reconstruction with respiratory motion-averaging (GRASP) and prior conventional breath-held Cartesian-sampled datasets (BH-VIBE) in same patients. In this HIPAA-compliant prospective study, 16 subjects underwent free-breathing continuous radial acquisition during Gd-EOB-DTPA injection, and had prior BH-VIBE exam available. Acquired data were reconstructed using motion-averaging GRASP approach, in which consecutive 84-spokes were grouped in each contrast-enhanced phase for a temporal resolution of ~14 seconds. Additionally, respiratory motion-resolved reconstruction was performed from the same k-space data, by sorting each contrast-enhanced phase into multiple respiratory motion states using compressed sensing algorithm named XD-GRASP, which exploits sparsity along both the contrast-enhancement and respiratory-state dimensions. Contrast-enhanced dynamic multi-phase XD-GRASP, GRASP, and BH-VIBE images were anonymized, pooled together in a random order and presented to two board-certified radiologists for independent evaluation of image quality, with higher score indicating more optimal exam. XD-GRASP reconstructions had significantly (all p<0.05) higher overall image quality scores compared to GRASP for early arterial (Reader 1: 4.3 ± 0.6 vs. 3.31 ± 0.6 ; Reader 2: 3.81 ± 0.8 vs. 3.38 ± 0.9) and late arterial (Reader 1: 4.5 ± 0.6 vs. 3.63 ± 0.6; Reader 2: 3.56 ± 0.5 vs. 2.88 ± 0.7) phases of enhancement for both readers. XD-GRASP also had higher overall image quality score in portal venous phase which was significant for Reader 1 (4.44 ± 0.5 vs. 3.75 ± 0.8; p=0.002). In addition, XD-GRASP had higher overall image quality score compared to BH-VIBE for early (Reader 1: 4.3±0.6 vs. 3.88±0.6; Reader 2: 3.81±0.8 vs. 3.50±1.0) and late (Reader 1: 4.5±0.6 vs. 3.44±0.6; Reader 2: 3.56±0.5 vs. 2.94±0.9) arterial phases. Free-breathing motion-resolved XD-GRASP reconstructions provide diagnostic high-quality multiphase images in patients undergoing Gd-EOB-DTPA-enhanced liver exam.