Concurrent renal adenocarcinoma and polycythemia in a dog.

Concurrent renal adenocarcinoma and polycythemia in a dog.
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狗并发肾腺癌和红细胞增多症。

DOI:
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发表时间:
1995
期刊:
The Journal of the American Animal Hospital Association
影响因子:
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通讯作者:
R. Culbertson
R. Culbertson
中科院分区:
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文献类型:
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作者:
SE Crow;DP Allen;Cj Murphy;R. Culbertson

文献摘要

被引文献

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并发肾腺癌和红细胞增多症被诊断为19个月大,雌性罗得西亚脊背。这是一个不寻常的早期表现,这种肿瘤,这是第二次报告的情况下,肾腺癌的狗不到两岁。先前在4只老年犬中报告了并发肾腺癌和红细胞增多症。在本报告的犬中,临床体征包括砖红色粘膜、嗜睡、周期性收缩期心脏杂音和视网膜血管充血。诊断时发现腹膜后巨大肿块及肺转移结节。红细胞计数、红细胞压积和血红蛋白浓度显著升高(分别为12,940,000个红细胞/微升; 73.2%;和26.6 g/dl)。组织学诊断为肾腺癌。红细胞增多症是由于肿瘤产生过多的促红细胞生成素。
Concurrent renal adenocarcinoma and polycythemia were diagnosed in a 19-month-old, female Rhodesian ridgeback. An unusually early presentation for this neoplasm, it is the second reported case of renal adenocarcinoma in a dog less than two years of age. Concurrent renal adenocarcinoma and polycythemia have been reported previously in four older dogs. In the dog of this report, clinical signs included brick-red mucous membranes, lethargy, a periodic systolic heart murmur, and engorged retinal vessels. A large retroperitoneal mass and pulmonary metastatic nodules were present at the time of diagnosis. Red blood cell count, packed cell volume, and hemoglobin concentration were greatly increased (12,940,000 red blood cells/microliter; 73.2%; and 26.6 g/dl, respectively). Histopathological diagnosis was renal adenocarcinoma. Polycythemia was the result of excessive erythropoietin production by the neoplasm.