Recurrence of sarcoidosis following interferon alpha therapy for chronic hepatitis C.
Recurrence of sarcoidosis following interferon alpha therapy for chronic hepatitis C.
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干扰素α治疗慢性丙型肝炎后结节病复发。
DOI：
10.2169/internalmedicine.35.376
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发表时间：
1996
影响因子：
1.2
通讯作者：
T. Manabe
中科院分区：
文献类型：
--
作者：
M. Nakajima;Y. Kubota;N. Miyashita;Y. Niki;T. Matsushima;T. Manabe
我们报告一例67岁男性患者，已知有结节病缓解史，在接受干扰素α（IFN-α）治疗慢性丙型肝炎5个月后复发结节病。胸部X线片显示双侧腮腺肿胀和双侧弥漫性网状结节性肺实质混浊。血清血管紧张素转换酶（ACE）水平和可溶性IL-2受体水平高，经支气管肺活检显示非干酪化肉芽肿。口服泼尼松龙后，实验室数据和胸部X线片的异常均消退。
We report a 67-year-old male patient with a known history of sarcoidosis in remission who had recurrent sarcoidosis following a five-month administration of interferon alpha (IFN-alpha) for chronic hepatitis C. He developed bilateral swelling of the parotid glands and bilateral diffuse reticulonodular pulmonary parenchymal opacities on chest roentgenograms. Serum angiotensin converting enzyme (ACE) levels and soluble IL-2 receptor levels were high and a transbronchial lung biopsy revealed noncaseating granulomas. The abnormalities on both laboratory data and chest roentgenograms were resolved after administration of oral prednisolone.
用重组α-干扰素治疗慢性丙型肝炎。
影响因子：
25.7
作者：
Davis,GL;Balart,LA;Schiff,ER;Lindsay,K;BodenheimerJr,HC;Perrillo,RP;Carey,W;Jacobson,IM;Payne,J;Dienstag,JL
通讯作者：
Dienstag,JL