Some premorbid characteristics related to breakdown in children with schizophrenic mothers
Some premorbid characteristics related to breakdown in children with schizophrenic mothers
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一些与精神分裂症母亲的孩子精神崩溃相关的病前特征
DOI：
10.1016/0022-3956(68)90022-8
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发表时间：
1968
影响因子：
4.8
通讯作者：
F. Schulsinger
中科院分区：
文献类型：
--
作者：
S. Mednick;F. Schulsinger
精神分裂症激发了大量的行为研究，这些研究的目标是提供有关精神分裂症病因的信息。然而，通过对经历过精神分裂症形成和发展过程的个体进行研究，可能很难分离出这些病因因素。这些人的行为可能会显着改变，以应对疾病的相关因素，如教育，经济和社会失败，院前，医院和医院后的药物治疗，单身，长期制度化，慢性疾病和纯粹的痛苦。在对非精神分裂症患者的研究中，这些相同的因素已被证明可测量地影响行为研究结果。如果研究人员使用与精神分裂症组等同的对照组来研究所有这些精神分裂症相关因素，那么任何观察到的差异都可以合理地归因于精神分裂症变量。但这样的对照组显然是不容易获得的。因此，在正常人和精神分裂症患者的比较中，通常很难判断报告的差异的哪一部分与精神分裂症有独特的相关性。例如，如果非精神病囚犯和正常人的比较产生了相同的差异，我们可能倾向于将精神分裂症的正常差异归因于制度化的影响，而不是精神分裂症患者的某些内在品质。
SCHIZOPHRENICS excite a good deal of behavioral research, the goal of much of this research is to produce information concerning the etiology of schizophrenia. It may be difficult, however, to isolate such etiological factors through studies carried out with individuals who have lived through the process of becoming and being schizophrenic. The behavior of these individuals may be markedly altered in response to correlates of the illness such as educational, economic and social failure, prehospital, hospital and post-hospital drug regimens, bachelorhood, long term institutionalization, chronic illness and sheer misery. In research with non-schizophrenics, these same factors have been shown to measurably affect behavioral research results. If researchers used control groups which were equated with their schizophrenic groups for all of these correlates of schizophrenia, then any observed differences could reasonably be ascribed to the variable of schizophrenia. But such control groups are apparently not readily available. Consequently, in comparisons of normals and schizophrenics, it is often difficult to judge what portion of the reported differences have unique relevance to schizophrenia. If, for example, comparisons of non-psychiatric prisoners and normals produced identical differences we might tend to attribute the schizophrenicnormal differences to the effects of institutionalization rather than some intrinsic quality of the schizophrenic.