Combined treatment with oral kanamycin and parenteral antibiotics for a case of persistent bacteremia and intestinal carriage with Campylobacter coli
Combined treatment with oral kanamycin and parenteral antibiotics for a case of persistent bacteremia and intestinal carriage with Campylobacter coli
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DOI：
10.2169/internalmedicine.47.1161
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发表时间：
2008-01-01
影响因子：
1.2
通讯作者：
Koike, Kazuhiko
中科院分区：
文献类型：
--
作者：
Okada, Haruka;Kitazawa, Takatoshi;Koike, Kazuhiko
大肠弯曲杆菌（Campylobacter coli，C. coli）是一种罕见的菌血症病原体，但在免疫功能低下的宿主中，C.大肠杆菌偶尔会引起菌血症，这可能是抗生素治疗无效的。本文报告一例C. X连锁无丙种球蛋白血症患者的大肠杆菌菌血症。尽管联合静脉注射抗生素治疗，但菌血症反复复发。C.肠粘膜活检标本中发现大肠杆菌，提示肠道携带和反复感染的储存库。口服卡马霉素加静脉注射抗生素成功根除了C。血液和肠道中的大肠杆菌
Campylobacter coli (C. coli) is a rare pathogen of bacteremia, but in immunocompromised hosts, C. coli occasionally causes bacteremia which can be refractory to antibiotic treatment. We report a case of C. coli bacteremia in a patient with X-linked agammaglobulinemia. Bacteremia relapsed repeatedly in spite of treatment with combined intravenous antibiotics. C. coli was observed in the biopsy specimens from the intestinal mucosa, suggesting intestinal carriage and reservoir of recurring infection. The addition of oral kamamycin with intravenous antibiotics was successful in eradicating C. coli from the blood and intestine.