Analyzing threshold pressure limitations in microfluidic transistors for self-regulated microfluidic circuits
Analyzing threshold pressure limitations in microfluidic transistors for self-regulated microfluidic circuits
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DOI：
10.1063/1.4769985
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发表时间：
2012-12-03
影响因子：
4
通讯作者：
Takayama, Shuichi
中科院分区：
文献类型：
--
作者：
Kim, Sung-Jin;Yokokawa, Ryuji;Takayama, Shuichi
本文揭示了微流体膜阀（mu MV）与电子晶体管之间电液类比的一个关键局限性。与具有相似开关阈值电压的典型晶体管不同，在液压mu mv中，即使对于相同的mu mv，开启和关闭的阈值压力也会显着不同并且可以改变，这取决于整体电路设计和操作条件。我们特别解释了关闭阈值压力的负值如何显着限制即使是简单的液压mu MV电路（如自主切换双阀微流体振荡器）的运行。这些认识对设计自我调节的微流体装置具有重要意义。(C) 2012年美国物理研究所。[http://dx.doi.org/10.1063/1.4769985]
This paper reveals a critical limitation in the electro-hydraulic analogy between a microfluidic membrane-valve (mu MV) and an electronic transistor. Unlike typical transistors that have similar on and off threshold voltages, in hydraulic mu MVs, the threshold pressures for opening and closing are significantly different and can change, even for the same mu MVs depending on overall circuit design and operation conditions. We explain, in particular, how the negative values of the closing threshold pressures significantly constrain operation of even simple hydraulic mu MV circuits such as autonomously switching two-valve microfluidic oscillators. These understandings have significant implications in designing self-regulated microfluidic devices. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4769985]