Preparation of monodispersed macroporous core-shell molecularly imprinted particles and their application in the determination of 2,4-dichlorophenoxyacetic acid.
Preparation of monodispersed macroporous core-shell molecularly imprinted particles and their application in the determination of 2,4-dichlorophenoxyacetic acid.
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DOI：
10.1016/j.chroma.2013.11.002
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发表时间：
2014-01
期刊：
影响因子：
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通讯作者：
Yongliang Liu;Yonghuan He;Yulong Jin;Yanyan Huang;Guoquan Liu;R. Zhao
中科院分区：
文献类型：
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作者：
Yongliang Liu;Yonghuan He;Yulong Jin;Yanyan Huang;Guoquan Liu;R. Zhao
多孔聚合物由于其可控的多孔结构有利于传质和结合能力而引起了广泛的关注。在这项工作中，通过表面引发原子转移自由基聚合（si-ATRP）制备了用于选择性识别2,4-二氯苯氧基乙酸（2,4-D）的新型大孔核壳分子印迹聚合物（MIP）。采用一步溶胀聚合法合成了单分散大孔聚甲基丙烯酸缩水甘油酯（PGMA）颗粒，并将其作为支撑基质制备表面MIP颗粒（PGMA@MIP）。由于位于内外表面的结合腔和大孔结构，PGMA@MIPs 显示出理想的模板去除和传质效率，从而对模板 2,4-D 具有出色的可及性和亲和力。此外，PGMA@MIPs 对 2,4-D 的选择性比 PGMA@NIPs 高得多。直接使用 PGMA@MIP 颗粒从自来水中选择性富集 2,4-D，2,4-D 的回收率为 90.0-93.4%，相对标准划分为 3.1-3.4% (n= 3)。大孔PGMA@MIPs还在四个萃取/反萃循环中对2,4-D具有稳定且优异的可重复使用性能。这种新型大孔核壳印迹材料可能成为从复杂样品中快速高效富集和分离目标化合物的有力工具。
Porous polymers have aroused extensive attention due to their controllable porous structure in favor of mass transfer and binding capacity. In this work, the novel macroporous core–shell molecularly imprinted polymers (MIP) for selective recognition of 2,4-dichlorophenoxyacetic acid (2,4-D) were prepared by surface initiated atom transfer radical polymerization (si-ATRP). By using one-step swelling and polymerization method, the monodispersed macroporous poly(glycidyl methacrylate) (PGMA) particles were synthesized and used as supporting matrix for preparing surface MIP particles (PGMA@MIP). Thanks to the inner and outer surface-located binding cavities and the macroporous structure, the PGMA@MIPs revealed desirable efficiency for template removal and mass transfer, and thus excellent accessibility and affinity toward template 2,4-D. Moreover, PGMA@MIPs exhibited much higher selectivity toward 2,4-D than PGMA@NIPs. PGMA@MIP particles were directly used to selectively enrich 2,4-D from tap water and the recoveries of 2,4-D were obtained as 90.0–93.4% with relative standard division of 3.1–3.4% (n= 3). The macroporous PGMA@MIPs also possessed steady and excellent reusable performance for 2,4-D in four extraction/stripping cycles. This novel macroporous core–shell imprinted material may become a powerful tool for rapid and efficient enrichment and separation of target compounds from the complicated samples.