Immunohistochemical demonstration of a testicular substance related to luteinizing hormone-releasing hormone.
Immunohistochemical demonstration of a testicular substance related to luteinizing hormone-releasing hormone.
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与黄体生成素释放激素相关的睾丸物质的免疫组织化学演示。
DOI：
10.1126/science.7022653
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Arimura,A
中科院分区：
文献类型：
--
作者：
Paull,WK;Turkelson,CM;Thomas,CR;Arimura,A
通过免疫组织化学方法，在大鼠睾丸间质细胞的细胞质中发现了与黄体生成素释放激素相关的物质。在许多生精小管中，精原细胞的细胞核也呈免疫阳性。睾丸匀浆的细胞质和核部分都含有免疫反应性化合物，该报告确定了哪些细胞类型含有这种物质。肽激素在靶细胞群细胞核内的定位可能表明其作用模式。
A substance related to luteinizing hormone-releasing hormone was demonstrated, by immunohistochemical procedures, in the cytoplasm of interstitial cells within the rat testes. In many seminiferous tubules, nuclei of spermatogonial cells were also immunopositive. Both cytoplasmic and nuclear fractions of testicular homogenates contain immunoreactive compounds, and this report identifies which cell types contain this substance. The localization of a peptide hormone within the nucleus of a target cell population may indicate its mode of action.