Binding kinetics of magnetic nanoparticles on latex beads and yeast cells studied by magnetorelaxometry
Binding kinetics of magnetic nanoparticles on latex beads and yeast cells studied by magnetorelaxometry
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DOI：
10.1016/j.jmmm.2004.11.122
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发表时间：
2005-03-01
影响因子：
2.7
通讯作者：
Trahms, L
中科院分区：
文献类型：
--
作者：
Eberbeck, D;Bergemann, C;Trahms, L
采用磁弛豫法对离子交换介导的磁性纳米粒子（MNP）与改性乳胶球和酵母细胞的结合进行了定量。通过拟合随后记录的弛豫曲线，提取结合反应的动力学。与胶乳和酵母细胞结合的具有弱离子交换基团的MNP的信号与胶乳珠或酵母细胞的浓度成线性比例，而具有强离子交换基团的MNP的信号与浓度的平方根成比例。后者的结合导致酵母细胞比前者MNP更强的聚集。(c)2004 Elsevier B.V.保留所有权利。
The ion exchange mediated binding of magnetic nanoparticles (MNP) to modified latex spheres and yeast cells was quantified using magnetorelaxometry. By fitting subsequently recorded relaxation curves, the kinetics of the binding reactions was extracted. The signal of MNP with weak ion exchanger groups bound to latex and yeast cells scales linearly with the concentration of latex beads or yeast cells whereas that of MNP with strong ion exchanger groups is proportional to the square root of concentration. The binding of the latter leads to a much stronger aggregation of yeast cells than the former MNP. (c) 2004 Elsevier B.V. All rights reserved.