Herpes simplex virus keratitis in children.
Herpes simplex virus keratitis in children.
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DOI：
10.1016/j.ajo.2004.04.027
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发表时间：
2004-09-01
影响因子：
4.2
通讯作者：
Paysse, EA
中科院分区：
文献类型：
--
作者：
Chong, EM;Wilhelmus, KR;Paysse, EA
目的：描述儿童和青少年单纯疱疹病毒（HSV）角膜炎的谱系和复发情况。设计：回顾性队列研究。方法：16 岁以下的 23 名患者在一个机构被诊断为 HSV 角膜炎。结果：所有儿童均表现为树枝状或点状上皮性角膜炎，14 名患者中基质性角膜炎与上皮性角膜炎同时发生。 （61%）。六名患者 (26%) 患有双侧 HSV 角膜炎。 11 名患者 (48%) 在首次记录的发病后平均 15 个月内出现复发性 HSV 角膜炎。 3名儿童出现弱视。结论：疱疹性角膜炎儿童可能双侧眼部受累，有复发性角膜炎和弱视的风险。 (C) 2004 年，Elsevier Inc. 保留所有权利。
PURPOSE: To describe the spectrum and recurrence of herpes simplex virus (HSV) keratitis in children and adolescents.DESIGN: Retrospective cohort study.METHODS: Twenty-three patients younger than age 16 years were diagnosed with HSV keratitis at one institution.RESULTS: All children presented with dendritic or punctate epithelial keratitis, and stromal keratitis occurred concurrently with epithelial keratitis in 14 patients (61%). Six patients (26%) had bilateral HSV keratitis. Eleven patients (48%) developed recurrent HSV keratitis at a median of 15 months after the first documented episode. Amblyopia occurred in three children.CONCLUSION: Children with herpetic keratitis may have bilateral ocular involvement and are at risk for recurrent keratitis and amblyopia. (C) 2004 by Elsevier Inc. All rights reserved.