Improved Shear Wave Group Velocity Estimation Method Based on Spatiotemporal Peak and Thresholding Motion Search.
Improved Shear Wave Group Velocity Estimation Method Based on Spatiotemporal Peak and Thresholding Motion Search.
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DOI：
10.1109/tuffc.2017.2652143
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发表时间：
2017-04
期刊：
影响因子：
--
通讯作者：
Urban MW
中科院分区：
文献类型：
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作者：
Amador Carrascal C;Chen S;Manduca A;Greenleaf JF;Urban MW
定量超声弹性成像越来越多地用于评估慢性肝病。许多研究报告了健康个体和不同阶段肝纤维化患者的肝剪切波速度值的范围。尽管如此，目前仍在努力通过评估影响组织剪切波速度值的因素来稳定定量超声弹性成像测量，这些因素包括食物摄入量、体重指数（BMI）、超声扫描仪、扫描协议、超声图像质量等。达到峰值时间（TTP）方法已常规用于测量剪切波速度。然而，仍然需要能够在存在噪声运动数据的情况下提供鲁棒的剪切波速度估计的方法。传统的TTP算法仅限于在不同空间位置的时间剖面中搜索最大运动。在这项研究中，提出了两个修改的剪切波速估计算法。第一种方法在空间和时间上搜索最大运动（时空峰值，STP）;第二种方法应用幅度滤波器（时空阈值，STTH）来选择运动幅度高于剪切波群速度估计阈值的点。两种方法（STP和STTH）在剪切波速度估计方面的精度高于体模中的TTP。此外，在14名健康受试者的队列中，与传统TTP相比，STP和STTH方法提高了剪切波速度测量精度和测量成功率。
Quantitative ultrasound elastography is increasingly being used in the assessment of chronic liver disease. Many studies have reported ranges of liver shear wave velocities values for healthy individuals and patients with different stages of liver fibrosis. Nonetheless, ongoing efforts exist to stabilize quantitative ultrasound elastography measurements by assessing factors that influence tissue shear wave velocity values, such as food intake, body mass index (BMI), ultrasound scanners, scanning protocols, ultrasound image quality, etc. Time-to-peak (TTP) methods have been routinely used to measure the shear wave velocity. However, there is still a need for methods that can provide robust shear wave velocity estimation in the presence of noisy motion data. The conventional TTP algorithm is limited to searching for the maximum motion in time profiles at different spatial locations. In this study, two modified shear wave speed estimation algorithms are proposed. The first method searches for the maximum motion in both space and time (spatiotemporal peak, STP); the second method applies an amplitude filter (spatiotemporal thresholding, STTH) to select points with motion amplitude higher than a threshold for shear wave group velocity estimation. The two proposed methods (STP and STTH) showed higher precision in shear wave velocity estimates compared to TTP in phantom. Moreover, in a cohort of 14 healthy subjects STP and STTH methods improved both the shear wave velocity measurement precision and the success rate of the measurement compared to conventional TTP.