Attempt at visualizing breast cancer with X-ray dark field imaging

Attempt at visualizing breast cancer with X-ray dark field imaging
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DOI:
10.1143/jjap.44.l528
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发表时间:
2005-01-01
期刊:
JAPANESE JOURNAL OF APPLIED PHYSICS PART 2-LETTERS & EXPRESS LETTERS
影响因子:
--
通讯作者:
Hirano, M
Hirano, M
中科院分区:
其他
文献类型:
--
作者:
Ando, M;Yamasaki, K;Hirano, M

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X射线暗场成像(DFI)可以清晰地显示2.8 mm厚的乳腺癌病理标本中的乳腺癌幻影和癌细胞巢、间质、脂肪组织、乳管、肌肉、间质中的胶原纤维和钙化。该系统包括一个布拉格非对称切割单色准直器和一个2.124毫米厚的Si 440劳厄衍射分析仪在35 keV。两个光学元件都是由硅晶体浮区制造的。在光子工厂的垂直摆动器光束线BL 14 B上,可获得33 mm(H)x 19.5 mm(V)的视图尺寸和10 μ m或更好的空间分辨率。
X-ray dark-field imaging (DFI) can clearly visualize breast cancer phantoms and cancer cell nests, stroma, fat tissue, ductus lactiferi, muscle, collagen fibers at stroma and calcification in a 2.8-mm-thick breast cancer pathological specimen. The system comprises a Bragg asymmetric-cut monochro-collimator and a 2.124-mm-thick Si 440 Laue diffraction analyzer at 35 keV. Both optical elements are Floating Zone made silicon crystals. The view size of 33 mm (H) x 19.5 mm (V) and the spatial resolution of 10 mu m or better are obtainable at the vertical wiggler beamline BL14B at the Photon Factory.