Microvessels of bulbar conjunctiva in UPTAH goats.
Microvessels of bulbar conjunctiva in UPTAH goats.
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UPTAH 山羊球结膜的微血管。
DOI：
10.1046/j.1525-1594.2003.07189.x
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发表时间：
2003
影响因子：
2.4
通讯作者：
K. Imachi
中科院分区：
文献类型：
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作者：
P. Dobsak;J. Vaskuo;A. Baba;T. Isoyama;I. Saito;J. Siègelovà;J. Jančík;H. Svačinová;K. Imachi
为直观观察人工心脏(TAH)植入术后微循环的变化，采用结膜血管内窥镜对2只山羊进行了长期随访。拍摄一小段平行小动脉和小静脉，在计算机图像程序(放大40倍)上进行分析。测量三个主要参数：小动脉直径、小静脉直径和动静脉比(A/V比)。胸腔内植入TAH为波动泵全人工心脏(UPTAH)，心输出量为100ml/kg/min。采用1/R生物反馈控制系统稳定外周血流动力学。我们的结果仅提供了有关球微血管形态的基本数据。主要发现是全身血管收缩的趋势，静脉侧更强烈(*P<；0.05在一只山羊)。我们没有观察到任何病理形态(如扭曲、曲张或淤泥)；这一结果可以归因于1/R对照方法的高效率。这些初步结果只应被认为是将广泛使用的临床结膜血管内窥镜检查方法应用于TAH的一种尝试。
Aiming to observe directly the microcirculation after total artificial heart (TAH) implantation, we performed a long-term follow-up in 2 goats using conjunctival angioscopy. A short segment of parallel arteriole and venule was photographed and analyzed on computer picture program (magnification 40x). Three main parameters were measured: arteriole diameter, venule diameter, and arteriovenous ratio (A/V ratio). The intrathoracically implanted TAH was the undulation pump total artificial heart (UPTAH) with cardiac output of 100 ml/kg/min. To stabilize the peripheral hemodynamics a 1/R biofeedback control system was used. Our results provided only elementary data about morphology of bulbar microvessels. The main finding was the tendency to general vasoconstriction, more intensive on the venous side (*P < 0.05 in one goat). We did not observe any pathological shapes (e.g., tortuosities, varicosities, or sludge); this result could be attributed to the high effectivity of 1/R control method. These preliminary results should be considered only as an attempt to apply the widely used clinical method of conjunctival angioscopy to the conditions of TAH.
DOI：
--
发表时间：
2009
期刊：
影响因子：
--
作者：
Y.Abe;K.Imachi
通讯作者：
K.Imachi