A MILD OXIDIZING REAGENT FOR ALCOHOLS AND 1,2-DIOLS - O-IODOXYBENZOIC ACID (IBX) IN DMSO
A MILD OXIDIZING REAGENT FOR ALCOHOLS AND 1,2-DIOLS - O-IODOXYBENZOIC ACID (IBX) IN DMSO
复制标题
DOI：
10.1016/0040-4039(94)80038-3
复制
发表时间：
1994-10-24
影响因子：
1.8
通讯作者：
SANTAGOSTINO, M
中科院分区：
文献类型：
--
作者：
FRIGERIO, M;SANTAGOSTINO, M
邻碘苯甲酸(IBX)能平稳地将伯醇和仲醇分别氧化成醛和酮。1，2-二醇可转化为α-酮醇或α-二酮，而不会使乙二醇C-C键发生氧化断裂。在室温下，IBX在DMSO溶液中很容易氧化，产率从好到定量不等。
o-Iodoxybenzoic acid (IBX) smoothly oxidizes primary and secondary alcohols to aldehydes and ketones, respectively. 1,2-Diols are converted to alpha-ketols or alpha-diketones without any oxidative cleavage of the glycol C-C bond. IBX oxidations are easily conducted in DMSO solution at room temperature, with yields ranging from good to quantitative.