Outcomes and treatment of obstetrical antiphospholipid syndrome in women with low antiphospholipid antibody levels
Outcomes and treatment of obstetrical antiphospholipid syndrome in women with low antiphospholipid antibody levels
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DOI：
10.1016/j.jri.2012.02.004
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发表时间：
2012-06-01
影响因子：
3.4
通讯作者：
Fain, Olivier
中科院分区：
文献类型：
--
作者：
Mekinian, Arsene;Loire-Berson, Priscille;Fain, Olivier
我们的目的是确定低水平抗磷脂抗体(APL)与抗磷脂综合征(APS)产科并发症的关系，并分析低APL患者常规抗磷脂抗体治疗的影响。为此，我们回顾了所有转诊到我们单位的不明原因妊娠发病率的患者(2003-2010年)的档案，并提供了APL测试结果。我们比较了符合札幌标准的APS患者(第1组)和APL滴度低于中间滴度的APS样产科并发症患者(第2组)。共纳入57例患者(第一组25例，第二组32例)。产科事件为复发性自然流产
Our objective was to determine whether there is a relationship between low antiphospholipid (aPL) antibody levels and the obstetrical complications of antiphospholipid syndrome (APS) and to analyze the impact of conventional APS treatment in patients with low aPL levels. To this end, we retrospectively reviewed the files of all patients referred to our unit (2003-2010) for unexplained pregnancy morbidity, with an aPL test result. We compared patients with APS confirmed by Sapporo criteria (Group 1) with patients with APS-like obstetrical complications with an aPL titer below the intermediate titer (Group 2). Overall, 57 patients were included (25 in Group 1:32 in Group 2). Obstetrical events were recurrent spontaneous abortion