Hybridization Reveals the Evolving Genomic Architecture of Speciation
Hybridization Reveals the Evolving Genomic Architecture of Speciation
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DOI：
10.1016/j.celrep.2013.09.042
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发表时间：
2013-11-01
期刊：
影响因子：
8.8
通讯作者：
Mullen, Sean P.
中科院分区：
文献类型：
--
作者：
Kronforst, Marcus R.;Hansen, Matthew E. B.;Mullen, Sean P.
在物种形成过程中，基因组分化的速度是未知的，这一过程的物理动力学也是未知的。在这里，我们比较了32只蝴蝶的全基因组序列，代表了来自杂交蝴蝶群落的5个物种，以检查全基因组的渐入模式，并推断在物种形成过程中分化是如何演变的。我们的分析表明，最初的分化仅限于基因组的一小部分，主要集中在已知的翅膀模式基因周围。随着时间的推移，分化发展迅速，这主要是由于新的分化区域的起源。此外，不同的基因组区域显示了选择和适应性渗入的特征，证明了物种内部的微观进化过程与跨宏观进化时间尺度的物种起源之间的联系。我们的研究结果提供了进化物种边界的独特全面的肖像，由于杂交在减少中性位点的分歧背景积累中起作用。
The rate at which genomes diverge during speciation is unknown, as are the physical dynamics of the process. Here, we compare full genome sequences of 32 butterflies, representing five species from a hybridizing Heliconius butterfly community, to examine genome-wide patterns of introgression and infer how divergence evolves during the speciation process. Our analyses reveal that initial divergence is restricted to a small fraction of the genome, largely clustered around known wing-patterning genes. Over time, divergence evolves rapidly, due primarily to the origin of new divergent regions. Furthermore, divergent genomic regions display signatures of both selection and adaptive introgression, demonstrating the link between microevolutionary processes acting within species and the origin of species across macroevolutionary timescales. Our results provide a uniquely comprehensive portrait of the evolving species boundary due to the role that hybridization plays in reducing the background accumulation of divergence at neutral sites.