The Impact of Substance Use Disorder on COVID-19 Outcomes.
The Impact of Substance Use Disorder on COVID-19 Outcomes.
复制标题
药物使用障碍对19种结果的影响。
DOI:
10.1176/appi.ps.202000534
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发表时间:
2021-05-01
期刊:
影响因子:
--
通讯作者:
Raji MA
中科院分区:
文献类型:
--
作者:
Baillargeon J;Polychronopoulou E;Kuo YF;Raji MA
The goal of this study was to examine the impact of substance use disorder on the risk of hospitalization, complications, and mortality in adult patients diagnosed with COVID-19 We conducted a propensity score (PS) matched double cohort study using data from the TriNetX Research Network database to identify 54,529 adult COVID-19 patients (≥18 years) diagnosed between February 20, 2020 and June 30, 2020. Our primary analysis—PS matched on demographic characteristics, diabetes, and obesity—showed that substance use disorder was associated with an increased risk of hospitalization (OR=1.84; 95% CI=1.69, 2.01), ventilator use (OR=1.45; 95% CI=1.22, 1.72) and mortality (OR=1.30; 95% CI=1.09, 1.56). Our findings suggest that COVID-19 patients with substance use disorders are at increased risk for adverse outcomes. The attenuation of ORs in the final model suggests that the observed risks may be partially mediated by drug-related respiratory and cardiovascular disease.
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影响因子:
4.2
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DOI:
10.1097/01.hdx.0000074519.43281.fa
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期刊:
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影响因子:
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