The cognitive paradigm ontology: design and application.

The cognitive paradigm ontology: design and application.
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DOI:
10.1007/s12021-011-9126-x
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发表时间:
2012-01
期刊:
影响因子:
3
通讯作者:
Laird AR
Laird AR
中科院分区:
医学4区
文献类型:
--
作者:
Turner JA;Laird AR

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提出了用于人类行为实验的认知范式本体论(CogPO)的基本结构。虽然实验心理学和认知神经科学文献可能以名称(例如,Stroop范式或Sternberg范式)或功能(工作记忆任务、视觉注意任务)来指代某些行为任务,但这些范式在呈现给受试者的刺激、来自受试者的预期反应以及给予受试者的指令方面可以有很大的不同。根据BrainMap项目(www.brainmap.org)近二十年来开发和使用的分类法来描述已发表的功能成像结果的关键组件,我们开发了一个本体,能够表示fMRI和PET文献中使用的认知范式的某些特征。认知范式本体论正在开发中,以符合基本形式本体论(BFO),并在可能的情况下与更大的本体论(如RadLex、NeuroLex或生物医学调查本体论(OBI))相协调。CogPO的关键组成部分包括对实验条件的表示,这些条件集中在所给出的刺激、所给出的指令和所请求的响应上。使用替代性的、甚至是竞争性的术语常常会阻碍科学发现。已经证明,根据刺激、反应和指令对范例进行分类,可以通过在多个范例水平上搜索相似性和对比来实现高级数据检索技术。CogPO的目标是开发、评估和分发认知范例的领域本体,以便在功能神经成像社区中应用和使用。
We present the basic structure of the Cognitive Paradigm Ontology (CogPO) for human behavioral experiments. While the experimental psychology and cognitive neuroscience literature may refer to certain behavioral tasks by name (e.g., the Stroop paradigm or the Sternberg paradigm) or by function (a working memory task, a visual attention task), these paradigms can vary tremendously in the stimuli that are presented to the subject, the response expected from the subject, and the instructions given to the subject. Drawing from the taxonomy developed and used by the BrainMap project (www.brainmap.org) for almost two decades to describe key components of published functional imaging results, we have developed an ontology capable of representing certain characteristics of the cognitive paradigms used in the fMRI and PET literature. The Cognitive Paradigm Ontology is being developed to be compliant with the Basic Formal Ontology (BFO), and to harmonize where possible with larger ontologies such as RadLex, NeuroLex, or the Ontology of Biomedical Investigations (OBI). The key components of CogPO include the representation of experimental conditions focused on the stimuli presented, the instructions given, and the responses requested. The use of alternate and even competitive terminologies can often impede scientific discoveries. Categorization of paradigms according to stimulus, response, and instruction has been shown to allow advanced data retrieval techniques by searching for similarities and contrasts across multiple paradigm levels. The goal of CogPO is to develop, evaluate, and distribute a domain ontology of cognitive paradigms for application and use in the functional neuroimaging community.