Agreement among sources of adult influenza vaccination in the age of immunization information systems.

Agreement among sources of adult influenza vaccination in the age of immunization information systems.
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DOI:
10.1016/j.vaccine.2021.10.041
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发表时间:
2021-11-16
期刊:
影响因子:
5.5
通讯作者:
Balasubramani GK
Balasubramani GK
中科院分区:
医学3区
文献类型:
--
作者:
Nowalk MP;D'Agostino HEA;Zimmerman RK;Saul SG;Susick M;Raviotta JM;Sax TM;Balasubramani GK

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许多疫苗接种研究依赖于自我报告的疫苗接种状况,存在固有的偏差。流感疫苗接种自我报告的准确性已定期评估,通常使用医疗记录作为黄金标准。电子病历(EMR)和免疫信息系统(IIS)的兴起以及社区药房成人疫苗接种的兴起表明有必要重新评估自我报告的疫苗接种状况。对四个季度(2016-2017 年至 2019-2020 年)门诊和住院流感疫苗有效性研究参与者的自我报告、州 IIS、卫生系统 EMR 和其他来源的疫苗接种数据进行了比较。计算来源之间的一致性以及敏感性和特异性。趋势测试评估了宾夕法尼亚州 - 全州 IIS (PA-SIIS) 数据完整性随时间的变化。以自我报告为黄金标准,与当地 EMR、PA-SIIS 和所有来源的一致性分别为 62%、77% 和 85%。 EMR 的敏感性为 42% (95% CI=41, 43),特异性为 91% (90, 92)。以 PA-SIIS 作为黄金标准,与当地 EMR 和所有来源的一致性分别为 77% 和 78%。所有来源的敏感性合计为 96% (95, 97),特异性为 (63% (62, 64)。随着时间的推移,IIS 中流感疫苗的接种情况并没有持续改善,儿童中显着增加 (P=0.001),工作年龄成人中没有变化,老年人中减少 (P=0.004)。然而,与EMR (43.3%) 和其他来源 (12.4%)。自我报告和 PA-SIIS 都是对实际疫苗接种情况的良好估计。当需要高精度数据时,例如疫苗有效性研究,应使用多个来源进行三角测量。
Many vaccination studies rely on self-reported vaccination status, with its inherent biases. Accuracy of influenza vaccination self-report has been evaluated periodically, typically using the medical record as the gold standard. The burgeoning of electronic medical records (EMRs) and immunization information systems (IISs) and the rise of adult vaccine administration in community pharmacies suggest the need for a reevaluation of self-reported vaccination status. Vaccination data from self-report, the state IIS, the health system EMR and other sources were compared for participants in outpatient and inpatient influenza vaccine effectiveness studies for four seasons (2016–2017 to 2019–2020). Agreement among the sources was calculated along with sensitivity and specificity. Tests for trend assessed changes in completeness of the Pennsylvania - Statewide IIS (PA-SIIS) data over time. With self-report as the gold standard, agreement with the local EMR, PA-SIIS, and all sources was 62%, 77% and 85%, respectively. Sensitivity of the EMR was 42% (95% CI=41, 43) and specificity was 91% (90, 92). With PA-SIIS-as the gold standard, agreement with the local EMR and all sources was 77% and 78%, respectively. Sensitivity of all sources combined was 96% (95, 97) and specificity was (63% (62, 64). Capture of influenza vaccinations in the IIS has not consistently improved over time, with a significant increase among children (P=0.001), no change among working-age adults and a decrease among older adults (P=0.004). However, PA-SIIS provided the largest percentage of verified vaccines (69.3%) compared with EMR (43.3%) and other sources (12.4%). Both self-report and PA-SIIS are good estimates of actual vaccine uptake. When high accuracy data are required, such as for vaccine effectiveness studies, triangulation using multiple sources should be conducted.
DOI: 10.1097/phh.0000000000000040
发表时间: 2015-05
期刊: Journal of public health management and practice : JPHMP
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