The impact of disease-related knowledge on perceptions of stigma among patients with Hepatitis C Virus (HCV) infection.
The impact of disease-related knowledge on perceptions of stigma among patients with Hepatitis C Virus (HCV) infection.
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DOI：
10.1371/journal.pone.0258143
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发表时间：
2021
期刊：
影响因子：
3.7
通讯作者：
Lo Re V 3rd
中科院分区：
文献类型：
--
作者：
Saine ME;Szymczak JE;Moore TM;Bamford LP;Barg FK;Forde KA;Schnittker J;Holmes JH;Mitra N;Lo Re V 3rd
大多数丙型肝炎病毒（HCV）感染患者都有一定程度的疾病相关的耻辱感。对疾病的误解可能导致与疾病相关的耻辱感。本研究的目的是评估HCV感染患者对HCV感染传播和自然病史的知识水平及其与HCV相关污名的关系。我们对费城265名丙型肝炎患者进行了横断面调查研究，采用丙型肝炎病耻感量表和全国健康与营养检查调查（NHANES）丙型肝炎随访调查（2001-2008）。通过线性回归评估HCV知识与HCV相关病耻感之间的关系。对HCV传播和自然病史的总体了解程度较高，有bbb80 %的参与者正确回答了11个项目中的≥9个（正确率中位数为9 [82%]），HIV/HCV合并感染和HCV单一感染参与者之间的HCV相关知识相似（p = 0.30）。较高的hcv相关知识水平与更高的hcv相关耻辱感相关(β, 2.34 （[95% CI, 0.51-4.17]; p = 0.013）。在调整了年龄、种族、民族、HIV状态、教育水平、HCV管理阶段、诊断时间和注射用药史后，结果相似。在这项研究中，丙型肝炎相关知识的增加与丙型肝炎病耻感的增加有关。临床医生在对患者进行丙型肝炎病毒感染教育时，可以考虑分配时间来解决对丙型肝炎病毒的常见误解，这可能会抵消更多丙型肝炎病毒相关知识带来的污名化影响。
Most patients with hepatitis C virus (HCV) infection perceive some degree of disease-related stigma. Misunderstandings about diseases may contribute to disease-related stigma. The objective of this study was to evaluate patient-level knowledge about HCV infection transmission and natural history and its association with HCV-related stigma among HCV-infected patients. We conducted a cross-sectional survey study among 265 patients with HCV in Philadelphia using the HCV Stigma Scale and the National Health and Nutrition Examination Survey (NHANES) Hepatitis C Follow-up Survey (2001–2008). The association between HCV knowledge and HCV-related stigma was evaluated via linear regression. Overall knowledge about HCV transmission and natural history was high, with >80% of participants answering ≥9 of 11 items correctly (median number of correct responses, 9 [82%]), HCV-related knowledge was similar between HIV/HCV-coinfected and HCV-monoinfected participants (p = 0.30). A higher level of HCV-related knowledge was associated with greater perceived HCV-related stigma (β, 2.34 ([95% CI, 0.51–4.17]; p = 0.013). Results were similar after adjusting for age, race, ethnicity, HIV status, education level, stage of HCV management, time since diagnosis, and history of injection drug use. In this study, increased HCV-related knowledge was associated with greater perceptions of HCV stigma. Clinicians may consider allotting time to address common misconceptions about HCV when educating patients about HCV infection, which may counterbalance the stigmatizing impact of greater HCV-related knowledge.
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影响因子：
3.7
作者：
Linas BP;Barter DM;Leff JA;Assoumou SA;Salomon JA;Weinstein MC;Kim AY;Schackman BR
通讯作者：
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DOI：
10.1016/j.drugpo.2021.103238
发表时间：
2021-10
期刊：
The International journal on drug policy
影响因子：
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作者：
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通讯作者：
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影响因子：
3.7
作者：
Akiyama MJ;Ross J;Rimawi F;Fox A;Jordan AO;Wiersema J;Litwin AH;Kaba F;MacDonald R
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