Clinical Manifestations of Ocular Toxoplasmosis
Clinical Manifestations of Ocular Toxoplasmosis
复制标题
DOI：
10.3109/09273948.2011.564068
复制
发表时间：
2011-04-01
影响因子：
3.3
通讯作者：
Brezin, Antoine
中科院分区：
文献类型：
--
作者：
Delair, Emmanuelle;Latkany, Paul;Brezin, Antoine
眼弓形虫病的临床表现进行了审查。先天性和急性获得性眼弓形虫病的表现包括视网膜瘢痕，活动期的白色病变，通常与玻璃体炎有关。并发症可包括纤维带、继发性浆液性或孔源性视网膜脱离、视神经炎和神经病、白内障、活动性感染期间眼内压升高和脉络膜新生血管膜。未经治疗的先天性弓形虫病的复发发生在青少年时期。出生时的表现不太严重，在子宫内和出生后第一年内疾病早期及时治疗的患者复发较少。在美国和巴西，有症状的先天性弓形虫病诊断时，严重的视网膜受累是常见的。急性获得性感染也可能并发弓形体视网膜脉络膜炎，最常见的复发时间接近收购。抑制性治疗可以减少复发性疾病。
Clinical manifestations of ocular toxoplasmosis are reviewed. Findings of congenital and acute acquired ocular toxoplasmosis include retinal scars, white-appearing lesions in the active phase often associated with vitritis. Complications can include fibrous bands, secondary serous or rhegmatogenous retinal detachments, optic neuritis and neuropathy, cataracts, increased intraocular pressure during active infection, and choroidal neovascular membranes. Recurrences in untreated congenital toxoplasmosis occur in teenage years. Manifestations at birth are less severe, and recurrences are fewer in those who were treated promptly early in the course of their disease in utero and in the first year of life. Severe retinal involvement is common at diagnosis of symptomatic congenital toxoplasmosis in the United States and Brazil. Acute acquired infections also may be complicated by toxoplasmic retinochoroiditis, with recurrences most common close to the time of acquisition. Suppressive treatment can reduce recurrent disease.