Intermolecular 1,5-dipolar cycloaddition reaction of tungsten-containing vinylazomethine ylides leading to seven-membered heterocycles.
Intermolecular 1,5-dipolar cycloaddition reaction of tungsten-containing vinylazomethine ylides leading to seven-membered heterocycles.
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DOI：
10.1002/chin.200628119
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发表时间：
2006-02
期刊：
影响因子：
5.2
通讯作者：
H. Kusama;Yasuo Suzuki;J. Takaya;N. Iwasawa
中科院分区：
文献类型：
--
作者：
H. Kusama;Yasuo Suzuki;J. Takaya;N. Iwasawa
由邻（烷-3-烯-1-炔基）苯基苯甲醛亚胺与钨羰基络合物反应生成的含钨乙烯基甲亚胺叶立德与烯酮缩醛进行分子间1，5-偶极环加成反应，以高产率得到氮杂卓并[1，2-a]吲哚衍生物。[5+2]或[3+2]环加合物的形成可以通过适当选择亲偶极试剂来控制。
Intermolecular 1,5-dipolar cycloaddition reaction of tungsten-containing vinylazomethine ylide, generated from o-(alk-3-en-1-ynyl)phenylbenzaldimines and tungsten carbonyl complex, with ketene acetals proceeds efficiently to give azepino[1,2-a]indole derivatives in good yield. Formation of [5+2] or [3+2] cycloadducts can be controlled by an appropriate choice of dipolarophile.