Pulmonary regurgitation is an important determinant of right ventricular contractile dysfunction in patients with surgically repaired tetralogy of Fallot
Pulmonary regurgitation is an important determinant of right ventricular contractile dysfunction in patients with surgically repaired tetralogy of Fallot
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DOI：
10.1161/01.cir.0000138397.60956.c2
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发表时间：
2004-09-14
期刊：
影响因子：
37.8
通讯作者：
Vogel, M
中科院分区：
文献类型：
--
作者：
Frigiola, A;Redington, AN;Vogel, M
由于右心室负荷条件异常，对四联症修复后肺动脉返流（PR）患者的右心室（RV）功能进行评估仍然具有挑战性。方法和结果我们检查了124例年龄为21 ± 11.4岁的患者，他们在3.7 ± 3.5年时接受了四联症修复术。经多普勒超声心动图检查，33例患者有轻度PR，22例中度PR，69例重度PR; 55例有显著三尖瓣返流（TR）。在RV和LV基础上测量心肌速度、等容收缩（IVA）期间的心肌加速度、应变和应变率。在四腔视图中测量三尖瓣环。在12导联心电图上测量QRS、QT、JT间期及其离散度。与对照组相比，所有患者的右心室IVA均较低（0.8+/-0.4 vs 1.8+/-0.5，P
Background-Evaluation of right ventricular (RV) function in patients with pulmonary regurgitation (PR) after tetralogy repair remains challenging because of abnormal RV loading conditions.Methods and Results-We examined 124 patients, aged 21+/-11.4 years, who had tetralogy repair at 3.7+/-3.5 years. By Doppler echocardiography, 33 patients had mild, 22 moderate, and 69 severe PR; 55 had significant tricuspid regurgitation (TR). Myocardial velocities, myocardial acceleration during isovolumic contraction (IVA), strain, and strain rate were measured at RV and LV base. Tricuspid valve annulus was measured in a 4-chamber view. QRS, QT, and JT intervals and their dispersions were measured from 12-lead electrocardiogram. IVA in the RV was lower in all patients compared with controls (0.8+/-0.4 versus 1.8+/-0.5, P